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Big Brain Holdings

North America, Florida, United States, Weston

Description

Big Brain Holdings is a prominent venture capital firm based in Weston, United States, with a distinct focus on the Solana ecosystem. Established as a dedicated investor in the blockchain space, the firm primarily targets early-stage projects built on the Solana blockchain, encompassing a wide array of sectors including decentralized finance (DeFi), GameFi, infrastructure, NFTs, and metaverse applications. Their investment thesis centers on identifying projects with strong technological foundations and significant growth potential within Solana's high-throughput, low-cost environment.

Big Brain Holdings employs a hands-on approach, often collaborating closely with founders to provide strategic guidance beyond just capital. Their portfolio reflects a commitment to the long-term growth of the Solana network, backing foundational protocols and innovative applications alike. The firm has demonstrated a prolific investment pace, with public records indicating participation in over 70 investments across various stages, predominantly seed rounds. They are frequently seen co-investing alongside other leading crypto-native venture funds, contributing to significant early-stage capital formation for promising Solana ventures.

While specific check sizes are not always publicly disclosed, Big Brain Holdings typically participates in seed rounds that often range from $1.5 million to $5 million in total capital raised. Their individual contributions are designed to provide meaningful early-stage funding, positioning them as a key enabler for nascent Solana projects. The firm's reputation within the crypto community is strong, underscored by a significant online presence, including over 1,000 followers on LinkedIn, reflecting their influence and active engagement in the Web3 investment landscape. Their strategic location in Weston, Florida, positions them within a growing hub for blockchain innovation.

Investor Profile

Big Brain Holdings has backed more than 159 startups, with 28 new investments in the last 12 months alone. The firm has led 14 rounds, about 9% of its total and boasts 0 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Seed, Pre Seed, Series A rounds (top funding stages).
  • Majority of deals are located in United States, Singapore, United Kingdom.
  • Strong thematic focus on Blockchain, Cryptocurrency, Web3.
  • Led 5 rounds in the past year.
  • Typical check size: $250K – $2M.

Stage Focus

  • Seed (67%)
  • Pre Seed (16%)
  • Series A (8%)
  • Series Unknown (6%)
  • Angel (1%)
  • Convertible Note (1%)
  • Initial Coin Offering (1%)
  • Private Equity (1%)
  • Post Ipo Equity (1%)

Country Focus

  • United States (45%)
  • Singapore (9%)
  • United Kingdom (8%)
  • Canada (7%)
  • Switzerland (5%)
  • Hong Kong (4%)
  • Israel (2%)
  • United Arab Emirates (2%)
  • South Korea (1%)
  • China (1%)

Industry Focus

  • Blockchain
  • Cryptocurrency
  • Web3
  • Gaming
  • Software
  • Financial Services
  • Information Technology
  • Decentralized Finance (Defi)
  • Artificial Intelligence (Ai)
  • Video Games
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Big Brain Holdings frequently co-invest with?

CV
Europe, England, United Kingdom, London
Co-Investments: 16
Borderless Capital
North America, Georgia, United States, Atlanta
Co-Investments: 10
Shima Capital
North America, NA - Puerto Rico, Puerto Rico, San Juan
Co-Investments: 15
OKX Ventures
Africa, Beau Vallon, Seychelles, Mahé
Co-Investments: 10
SV
North America, New York, United States, Brooklyn
Co-Investments: 12
Mirana
Asia, Hong Kong Island, Hong Kong, Hong Kong
Co-Investments: 9
GSR
Europe, England, United Kingdom, London
Co-Investments: 13
Animoca Brands
Asia, Hong Kong Island, Hong Kong, Cyberport
Co-Investments: 9
Foresight Ventures
Asia, Central Region, Singapore, Singapore
Co-Investments: 11
The Spartan Group
Asia, Central Region, Singapore, Singapore
Co-Investments: 12

Which angels does Big Brain Holdings often collaborate with?

Gabby Dizon
Asia, Rizal, Philippines, Pasig
Shared Deals: 3
D.
North America, Delaware, United States, Delaware City
Shared Deals: 3
Balaji Srinivasan
Asia, Central Region, Singapore, Singapore
Shared Deals: 4
RC
North America, United States
Shared Deals: 3
PT
North America, New York, United States, New York
Shared Deals: 4
DCF GOD
North America, California, United States
Shared Deals: 3
AY
North America, California, United States
Shared Deals: 8
SB
North America, California, United States, San Francisco
Shared Deals: 4
RG
North America, California, United States, San Francisco
Shared Deals: 4
SR
North America, California, United States, San Francisco
Shared Deals: 5

What are some of recent deals done by Big Brain Holdings?

Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.

Artificial Intelligence (AI)Decentralized Finance (DeFi)Service Industry
Pre SeedOct 16, 2025
Amount Raised: $3,000,000

Legend. trade is a crypto trading company by decentralized exchange.

Decentralized Finance (DeFi)
Pre SeedOct 16, 2025
Amount Raised: $1,500,000

Bulk is an online B2B trading platform that connects buyers and suppliers for bulk commodities and products.

Trading Platform
SeedSep 24, 2025
Amount Raised: $8,000,000
BIO Protocol

New York, New York, United States

BIO Protocol is a pioneering platform that uses blockchain technology to transform early-stage scientific research finance.

BiotechnologyBlockchainFinance
SeedSep 17, 2025
Amount Raised: $6,900,000
Helius Medical Technologies

Newtown, Pennsylvania, United States

Helius Medical Technologies is a neurotech company focused on neurological wellness.

BiotechnologyHealth CareHealth Diagnostics
Post Ipo EquitySep 15, 2025
Amount Raised: $500,000,000

Reflect enables the issuance and redemption of decentralized strategy-backed stablecoins on SVM-based networks.

BlockchainCryptocurrencyDecentralized Finance (DeFi)
SeedSep 3, 2025
Amount Raised: $3,750,000
Hemi Labs

New Castle, Delaware, United States

Hemi Labs is a blockchain platform provides scaling, security, and interoperability.

BitcoinBlockchainEthereumWeb3
SeedAug 26, 2025
Amount Raised: $15,000,000
Mill City Venture III

Wayzata, Minnesota, United States

Mill City Venture III is a company that offers business investment services.

LendingReal Estate InvestmentVenture Capital
Post Ipo EquityJul 28, 2025
Amount Raised: $450,000,000
Upexi

Henderson, Nevada, United States

Upexi is a multi-faceted brand owner that focuses on direct-to-consumer and Amazon brands.

Consumer GoodsE-CommerceRetail
Post Ipo DebtJul 11, 2025
Amount Raised: $150,000,000
Sphinx

Denver, Colorado, United States

Sphinx offers a platform for trading real world assets using perpetual swaps.

Financial ServicesFinTechSoftware
Pre SeedJun 24, 2025
Amount Raised: $2,000,000