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Breakout Labs

North America, California, United States, San Francisco

Description

Breakout Labs, an initiative of the Thiel Foundation, stands as a distinctive early-stage funder based in San Francisco, United States. Launched in 2011, its core mission is to bridge the critical gap between groundbreaking scientific research and commercial viability, supporting companies that are often deemed too nascent or high-risk for traditional venture capital. Unlike conventional investors, Breakout Labs provides non-dilutive funding, meaning they do not take equity in the companies they support, allowing founders to retain full ownership of their intellectual property and ventures. This unique model is particularly attractive to deep tech startups requiring substantial upfront capital for R&D without immediate pressure for commercial returns.

The organization's investment thesis centers on high-impact scientific and technological breakthroughs across a diverse range of sectors. Their portfolio spans areas such as food science, biomedicine, clean energy, advanced materials, robotics, and artificial intelligence. Breakout Labs seeks out projects with significant scientific hurdles but also immense potential to revolutionize industries or solve pressing global challenges. They act as a crucial catalyst, providing not only financial backing but also access to a robust network of scientific advisors, mentors, and resources to help these nascent companies navigate the complex journey from lab to market.

Since its inception, Breakout Labs has played a pivotal role in nurturing a new generation of scientific enterprises. They typically provide up to $350,000 in initial non-dilutive funding to their portfolio companies, a substantial sum designed to enable critical early-stage experimentation and development. As of 2017, Breakout Labs had supported over 50 companies, collectively disbursing more than $15 million to accelerate the development of innovative technologies. This consistent support underscores their commitment to fostering radical scientific innovation and transforming ambitious research into tangible, impactful products and services.

Investor Profile

Breakout Labs has backed more than 38 startups, with 0 new investments in the last 12 months alone. The firm has led 13 rounds, about 34% of its total and boasts 4 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Seed, Grant, Series Unknown rounds (top funding stages).
  • Majority of deals are located in United States.
  • Strong thematic focus on Biotechnology, Health Care, Manufacturing.
  • Typical check size: $100K – $350K.

Stage Focus

  • Seed (58%)
  • Grant (29%)
  • Series Unknown (5%)
  • Private Equity (3%)
  • Pre Seed (3%)
  • Series A (3%)

Country Focus

  • United States (100%)

Industry Focus

  • Biotechnology
  • Health Care
  • Manufacturing
  • Therapeutics
  • Chemical
  • Medical
  • Medical Device
  • Beauty
  • Sensor
  • Pharmaceutical
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Breakout Labs frequently co-invest with?

The Thiel Foundation
North America, California, United States, San Francisco
Co-Investments: 3
Sequoia Capital
North America, California, United States, Menlo Park
Co-Investments: 2
Cantos
North America, California, United States, San Francisco
Co-Investments: 1
Breakout Ventures
North America, California, United States, San Francisco
Co-Investments: 1
ICONIQ Capital
North America, California, United States, San Francisco
Co-Investments: 2
Boston Millennia Partners
North America, Massachusetts, United States, Boston
Co-Investments: 1
Artis Ventures (AV)
North America, California, United States, San Francisco
Co-Investments: 2
Horizons Ventures
Asia, Hong Kong Island, Hong Kong, Hong Kong
Co-Investments: 2
Propel(X)
North America, California, United States, San Francisco
Co-Investments: 2
Alumni Ventures
North America, New Hampshire, United States, Manchester
Co-Investments: 1

Which angels does Breakout Labs often collaborate with?

KJ
North America, New York, United States, New York
Shared Deals: 1
AB
North America, California, United States, San Francisco
Shared Deals: 1
EK
North America, California, United States
Shared Deals: 1
LB
North America, United States
Shared Deals: 2
FM
North America, New York, United States, New York
Shared Deals: 1

What are some of recent deals done by Breakout Labs?

Napigen

Wilmington, Delaware, United States

NAPIGEN is a biotechnology company that addresses novel genome engineering of various organisms such as plants, microbes, and animals.

AgricultureAgTechBiotechnology
SeedJul 12, 2022
Amount Raised: $7,850,000
Glyscend Therapeutics

Baltimore, Maryland, United States

Glyscend develops a revolutionary approach to treating type 2 diabetes.

BiopharmaBiotechnologyCosmetic SurgeryLandscapingMedicalPharmaceuticalTherapeutics
SeedJul 24, 2019
Curie Co

New York, New York, United States

Curie Co is a life science company that engineers enzymes and marine biomaterials to replace harmful and banned chemicals.

BeautyBiotechnologyChemical
SeedJul 1, 2019
Napigen

Wilmington, Delaware, United States

NAPIGEN is a biotechnology company that addresses novel genome engineering of various organisms such as plants, microbes, and animals.

AgricultureAgTechBiotechnology
SeedApr 30, 2019
DropGenie

Boston, Massachusetts, United States

Scalable gene editing at the resolution of a single patient

Biotechnology
SeedApr 29, 2019
Nuclease Probe Technologies

Boston, Massachusetts, United States

Nuclease Probe Technologies is a platform for the early diagnosis of infectious diseases.

SeedMar 7, 2019
Amount Raised: $500,000
scibac

Burlingame, California, United States

SciBac is a developer of biotherapeutics intended to treat antibiotic diseases.

BiotechnologyHealth CareTherapeutics
SeedOct 10, 2018
Orion BioScience

Kansas City, Missouri, United States

Orion BioScience specializes in the fields of biotechnology and life science.

Biotechnology
SeedOct 1, 2018
Pelitex

Syracuse, New York, United States

Pelitex is a product development and technology licensing firm.

SeedAug 11, 2018
Phase Two Chemicals

Lowell, Massachusetts, United States

Phase Two Chemicals is a clean chemistry company developing breakthrough technology for on-site hydrogen peroxide production.

ChemicalCleanTechManufacturing
SeedMay 9, 2018