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Catalyst Health Ventures

North America, Massachusetts, United States, Boston

Description

Catalyst Health Ventures (CHV) is a well-established Boston-based venture capital firm with a clear focus on early-stage healthcare innovation. Since its inception in 2000, CHV has dedicated its efforts to identifying and funding disruptive solutions that address significant unmet needs within the healthcare sector. The firm primarily targets companies in the medical device, diagnostics, and digital health spaces, seeking out promising ventures poised to transform patient care and industry practices.

CHV's investment strategy centers on providing crucial early-stage capital, typically participating in Seed and Series A funding rounds. Their initial investments generally fall within a range of $1 million to $5 million, reflecting their commitment to supporting nascent companies through their critical initial growth phases. Beyond the initial cheque, Catalyst Health Ventures is known for reserving substantial capital for follow-on investments, demonstrating a long-term commitment to their portfolio companies' success and growth trajectory.

The firm boasts a robust track record, having invested in over 40 companies since its founding. This extensive portfolio underscores CHV's deep experience and network within the healthcare industry. Furthermore, their strategic support and guidance have enabled their portfolio companies to collectively secure over $1.5 billion in follow-on capital from other leading healthcare investors, highlighting CHV's ability to identify and nurture ventures that attract significant further investment and achieve substantial milestones. As an active participant in the vibrant Boston healthcare ecosystem, CHV continues to be a key player in fostering innovation in the sector.

Investor Profile

Catalyst Health Ventures has backed more than 46 startups, with 3 new investments in the last 12 months alone. The firm has led 24 rounds, about 52% of its total and boasts 7 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series A, Series C rounds (top funding stages).
  • Majority of deals are located in United States.
  • Strong thematic focus on Health Care, Medical Device, Medical.
  • Led 2 rounds in the past year.
  • Typical check size: $1M – $5M.

Stage Focus

  • Series B (35%)
  • Series A (30%)
  • Series C (13%)
  • Series Unknown (9%)
  • Seed (7%)
  • Debt Financing (2%)
  • Series D (2%)
  • Series E (2%)

Country Focus

  • United States (100%)

Industry Focus

  • Health Care
  • Medical Device
  • Medical
  • Biotechnology
  • Health Diagnostics
  • Hospital
  • Software
  • Oncology
  • Wellness
  • Information Technology
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Catalyst Health Ventures frequently co-invest with?

Rainfall Ventures
North America, New York, United States, New York
Co-Investments: 3
SG
North America, Massachusetts, United States, Stoneham
Co-Investments: 7
Schooner Capital
North America, Massachusetts, United States, Boston
Co-Investments: 3
Tribeca Venture Partners
North America, New York, United States, New York
Co-Investments: 3
Ascension Ventures
North America, Missouri, United States, Clarkton
Co-Investments: 5
Excelestar Ventures
North America, Massachusetts, United States, Andover
Co-Investments: 8
Mass Medical Angels
North America, Massachusetts, United States, Boston
Co-Investments: 3
Lerer Hippeau
North America, New York, United States, New York
Co-Investments: 3
LV
North America, Massachusetts, United States, Boston
Co-Investments: 3
AV
North America, California, United States, San Francisco
Co-Investments: 3

Which angels does Catalyst Health Ventures often collaborate with?

SK
North America, California, United States, San Francisco
Shared Deals: 2
CB
North America, United States
Shared Deals: 1
RG
North America, Florida, United States, Fort Myers
Shared Deals: 1

What are some of recent deals done by Catalyst Health Ventures?

Lena Health

Houston, Texas, United States

AI-augmented Text-based Health Assistant for patients

Artificial Intelligence (AI)Health Care
SeedApr 22, 2025
Amount Raised: $2,000,000
Esperto Medical

Orange, California, United States

Esperto's patented technology uses sound waves to measure blood pressure without an inflating cuff

Health DiagnosticsMedical Device
Series AOct 24, 2024
Venova Medical

Los Gatos, California, United States

Venova Medical develops vascular access systems for patients requiring renal replacement therapy.

Health CareMedicalMedical DeviceTherapeutics
Series BSep 4, 2024
Amount Raised: $30,000,000
Brixton Biosciences

Cambridge, Massachusetts, United States

Brixton Biosciences is a clinical-stage life sciences company that develops novel therapies for treating pain.

BiotechnologyInformation TechnologyLife Science
Series BMay 14, 2024
Amount Raised: $33,000,000
AtaCor Medical

San Clemente, California, United States

AtaCor Medical is a medical device maker.

Health CareMedical Device
Series CApr 24, 2024
Amount Raised: $28,000,000
Avive Solutions

Brisbane, California, United States

Avive Solutions develops an automated external defibrillator and software solutions.

Health CareMedical DeviceWellness
Series BFeb 14, 2024
Amount Raised: $56,500,000
Instylla

Waltham, Massachusetts, United States

Instylla is a medical equipment supplier that provides liquid embolics of the next generation for interventional radiology.

BiotechnologyCommercialMedical Device
Series CAug 15, 2023
Amount Raised: $30,000,000
Rejoni

Bedford, Massachusetts, United States

Rejoni develops solutions designed to minimize the short and long-term risks associated with gynecological procedures.

BiotechnologyHealth CareHealth DiagnosticsMedical Device
Series BDec 7, 2022
Amount Raised: $26,250,000
Avive Solutions

Brisbane, California, United States

Avive Solutions develops an automated external defibrillator and software solutions.

Health CareMedical DeviceWellness
Series AMar 16, 2022
Amount Raised: $22,000,000
Epitel

Salt Lake City, Utah, United States

Epitel is empowering clinicians, patients, and caregivers who live with or care for neurological disorders with wearables and powerful AI.

Emergency MedicineHealth CareHealth DiagnosticsHome Health CareHospitalMedicalMedical DevicemHealthNeuroscience
Series AFeb 16, 2022
Amount Raised: $12,500,000