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First Star Ventures

North America, Massachusetts, United States, Cambridge

Description

First Star Ventures is a Cambridge, Massachusetts-based venture capital firm established in 2015, dedicated to backing visionary, technical founders who are inventing the future. The firm primarily focuses on early-stage investments, specializing in Seed and Series A rounds. Their investment thesis centers on deep tech, frontier tech, and disruptive innovation, seeking out companies that are pushing the boundaries of technology and science.

The firm's investment strategy often involves leading or co-leading initial funding rounds. First Star Ventures typically deploys an initial check ranging from $1 million to $5 million, reflecting their commitment to providing substantial early capital to promising ventures. They actively seek out founders emerging from top-tier research institutions such as MIT, Harvard, Stanford, and Caltech, underscoring their emphasis on scientific and engineering excellence.

In 2021, First Star Ventures successfully closed its second fund, First Star Ventures Fund II, LP, with a total capital commitment of $60 million. This significant fund size enables them to provide robust support to their portfolio companies. As of early 2024, the firm has made over 45 investments, demonstrating a consistent track record of identifying and backing innovative startups across various sectors, including artificial intelligence, robotics, biotechnology, and advanced materials. Their approach is characterized by conviction and a deep understanding of the technical challenges and opportunities within their target markets.

Investor Profile

First Star Ventures has backed more than 54 startups, with 4 new investments in the last 12 months alone. The firm has led 8 rounds, about 15% of its total and boasts 9 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Seed, Series A, Pre Seed rounds (top funding stages).
  • Majority of deals are located in United States, Canada, Israel.
  • Strong thematic focus on Software, Artificial Intelligence (AI), Biotechnology.
  • Typical check size: $1M – $5M.

Stage Focus

  • Seed (63%)
  • Series A (15%)
  • Pre Seed (11%)
  • Series Unknown (7%)
  • Series B (2%)
  • Debt Financing (2%)

Country Focus

  • United States (83%)
  • Canada (13%)
  • Israel (4%)

Industry Focus

  • Software
  • Artificial Intelligence (Ai)
  • Biotechnology
  • Analytics
  • Information Technology
  • Saas
  • Enterprise Software
  • Predictive Analytics
  • Machine Learning
  • Logistics
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does First Star Ventures frequently co-invest with?

Munich Re Ventures
North America, New Jersey, United States, Princeton
Co-Investments: 4
Wireframe Ventures
North America, California, United States, Mill Valley
Co-Investments: 3
Bain Capital Ventures
North America, California, United States, San Francisco
Co-Investments: 4
A.Capital Ventures
North America, California, United States, Menlo Park
Co-Investments: 2
Dynamo
North America, Tennessee, United States, Chattanooga
Co-Investments: 2
ff Venture Capital
North America, New York, United States, New York
Co-Investments: 2
645 Ventures
North America, New York, United States, New York
Co-Investments: 2
Schematic Ventures
North America, California, United States, San Francisco
Co-Investments: 2
Energy Impact Partners
North America, New York, United States, New York
Co-Investments: 2
Lerer Hippeau
North America, New York, United States, New York
Co-Investments: 2

Which angels does First Star Ventures often collaborate with?

LW
North America, California, United States, San Francisco
Shared Deals: 1
GT
North America, California, United States, San Francisco
Shared Deals: 1
CQ
North America, New York, United States, New York
Shared Deals: 1
GB
North America, California, United States, San Francisco
Shared Deals: 1
JA
North America, California, United States, San Francisco
Shared Deals: 1
Xiaolai Li
Asia, Beijing, China, Beijing
Shared Deals: 2
WW
North America, California, United States, Palo Alto
Shared Deals: 1
BS
North America, New York, United States, New York
Shared Deals: 1
AN
North America, California, United States, San Francisco
Shared Deals: 1
TP
North America, California, United States, San Francisco
Shared Deals: 1

What are some of recent deals done by First Star Ventures?

Bedrock Energy

Austin, Texas, United States

Bedrock Energy develops drilling technology and advanced subsurface simulation software to enable geothermal heating and cooling.

CommercialConstruction
Series AJan 22, 2025
Amount Raised: $12,000,000
Phaseshift Technologies

Toronto, Ontario, Canada

Accelerating the development and deployment of next-generation engineering materials through AI and Computational Materials Engineering.

Advanced MaterialsArtificial Intelligence (AI)Information TechnologyMachine LearningQuantum Computing
SeedOct 21, 2024
Amount Raised: $2,963,704
Bot Auto

Houston, Texas, United States

Transforming American Transportation with Autonomous Trucks

AutomotiveAutonomous VehiclesTransportation
SeedSep 26, 2024
Amount Raised: $20,000,000
Enzymit

Ness Ziona, HaMerkaz, Israel

Enzymit is a bioproduction platform company based on computational protein design and ‘cell-free’ enzymatic manufacturing technology

BiotechnologyLife ScienceTherapeutics
Series ASep 25, 2024
Amount Raised: $10,000,000
Zanskar

Provo, Utah, United States

Zanskar develops a predictive platform informed by massive data for discovering previously unknown geothermal resources.

AnalyticsGreenTechInformation TechnologyPredictive AnalyticsRenewable Energy
Series BMay 6, 2024
Amount Raised: $30,000,000
Bedrock Energy

Austin, Texas, United States

Bedrock Energy develops drilling technology and advanced subsurface simulation software to enable geothermal heating and cooling.

AutomotiveAutonomous VehiclesCommercial
SeedOct 11, 2023
Amount Raised: $8,500,000
Salient

Cambridge, Massachusetts, United States

Salient combines novel ocean and land-surface data with AI and climate expertise to deliver the world’s most accurate S2S weather forecasts.

Software
SeedJun 27, 2023
Amount Raised: $3,000,000
Blumen Systems

San Francisco, California, United States

Blumen builds software powering clean energy development and mineral exploration.

Artificial Intelligence (AI)EnergySoftware
SeedApr 4, 2023
Amount Raised: $1,250,000
Genialis

Boston, Massachusetts, United States

Genialis is a computational precision medicines company that develops a clinical biomarker discovery platform.

BioinformaticsBiotechnologyHealth CareMedicalPrecision Medicine
Series AMar 29, 2023
Amount Raised: $13,000,000
Robigo

Cambridge, Massachusetts, United States

Robigo is a biomanufacturing company engineering microbes to create more sustainable crop protection solutions.

AgricultureBiotechnologyEnvironmental Engineering
SeedFeb 15, 2023
Amount Raised: $6,850,000