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Headwater Ventures

North America, Minnesota, United States, Minneapolis

Description

Headwater Ventures is a Minneapolis-based venture capital firm dedicated to investing in the modernization of health and care. Established in 2021, the firm focuses on early-stage companies, typically from Seed to Series A, that are leveraging technology and innovative business models to transform the healthcare landscape. With a notable Fund I of $100 million, Headwater Ventures positions itself as a significant player in the health tech investment space, aiming to back ventures that promise to enhance accessibility, efficiency, and equity within the healthcare system.

The firm's investment thesis is sharply defined, targeting companies across several critical areas. These include digital health solutions, tech-enabled services that streamline care delivery, innovations in care delivery models, initiatives promoting health equity, and advancements in data and artificial intelligence applications within healthcare. Headwater Ventures seeks out founders who are not only building disruptive technologies but are also deeply committed to solving complex challenges in health and care, emphasizing a partnership approach with its portfolio companies to foster growth and market penetration.

Regarding investment size, Headwater Ventures typically deploys initial capital ranging from $1 million to $5 million. This range is consistent with their focus on Seed and Series A rounds, allowing them to provide meaningful early-stage funding while reserving capital for follow-on investments as their portfolio companies achieve key milestones. The firm's strategic capital deployment is designed to support companies through critical development phases, from product-market fit to scaling operations, ensuring they have the resources to achieve their transformative goals in the health sector.

Headwater Ventures' commitment extends beyond mere capital provision; they actively engage with their portfolio, leveraging their deep industry expertise and network to guide companies through the complexities of the healthcare market. Their strategic investments underscore a vision for a more integrated, efficient, and patient-centric future for health and care, reflecting a proactive stance in shaping the next generation of healthcare solutions.

Investor Profile

Headwater Ventures has backed more than 25 startups, with 3 new investments in the last 12 months alone. The firm has led 0 rounds, about 0% of its total and boasts 1 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Seed, Pre Seed, Series A rounds (top funding stages).
  • Majority of deals are located in United States.
  • Strong thematic focus on Health Care, Software, Medical.
  • Typical check size: $1M – $5M.

Stage Focus

  • Seed (64%)
  • Pre Seed (20%)
  • Series A (12%)
  • Series Unknown (4%)

Country Focus

  • United States (100%)

Industry Focus

  • Health Care
  • Software
  • Medical
  • Artificial Intelligence (Ai)
  • Wellness
  • Fitness
  • Social
  • Health Diagnostics
  • Machine Learning
  • Telehealth
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Headwater Ventures frequently co-invest with?

Techstars
North America, Colorado, United States, Boulder
Co-Investments: 10
GSR Ventures
North America, California, United States, Menlo Park
Co-Investments: 2
City Light Capital
North America, New York, United States, New York
Co-Investments: 2
8VC
North America, California, United States, San Francisco
Co-Investments: 2
Human Ventures
North America, New York, United States, New York
Co-Investments: 2
DNA Capital
South America, Sao Paulo, Brazil, São Paulo
Co-Investments: 2
MaC Venture Capital
North America, Texas, United States, Abilene
Co-Investments: 2
New Stack Ventures
North America, Illinois, United States, Chicago
Co-Investments: 2
AA
North America, New York, United States, New York
Co-Investments: 2
Matchstick Ventures
North America, Colorado, United States, Boulder
Co-Investments: 3

Which angels does Headwater Ventures often collaborate with?

TW
North America, California, United States, San Francisco
Shared Deals: 1
AG
North America, California, United States, San Francisco
Shared Deals: 1
AL
North America, California, United States
Shared Deals: 1
AJ
North America, California, United States, San Francisco
Shared Deals: 1
TF
North America, Texas, United States, Dallas
Shared Deals: 1
EY
North America, California, United States, Santa Clara
Shared Deals: 1

What are some of recent deals done by Headwater Ventures?

Affineon Health

Denver, Colorado, United States

Healthcare is an AI inbox platform that automates administrative tasks for healthcare providers.

Health CareOffice AdministrationPaaS
SeedFeb 3, 2025
Amount Raised: $5,000,000
Affineon Health

Denver, Colorado, United States

Healthcare is an AI inbox platform that automates administrative tasks for healthcare providers.

Health CareOffice AdministrationPaaS
SeedOct 2, 2024
Ferrum Health

San Francisco, California, United States

Ferrum Health is a developer of an enterprise IT and AI patient safety platform for health systems.

Artificial Intelligence (AI)Health CareSoftware
Series ASep 19, 2024
Amount Raised: $16,000,000
Andy AI

San Francisco, California, United States

Andy is AI software that completes documentation for nurses during home visits.

Home Health Care
Pre SeedFeb 27, 2024
Amount Raised: $500,000
Piction Health

Boston, Massachusetts, United States

Piction Health uses telehealth technology to provide dermatology services, focusing on accessible skin care solutions.

Artificial Intelligence (AI)Health CareMedicalmHealthTelehealth
SeedJan 16, 2024
Amount Raised: $6,000,000
Mirza

New York, New York, United States

Mirza develops a FinTech platform to deliver tax-efficient employer stipends to a network of caregivers.

FinTechInformation TechnologyInsurTechProfessional Services
SeedAug 18, 2023
Amount Raised: $3,599,500
Venteur

Berkeley, California, United States

Venteur helps businesses to provide more affordable and personalized health insurance options to their employees.

Artificial Intelligence (AI)Employee BenefitsFinanceFinancial ServicesHealth CareInsuranceInsurTechMarketplace
SeedAug 16, 2023
Amount Raised: $7,600,000
Elion

New York, New York, United States

Elion is a digital health software marketplace for healthcare providers.

Health CareInformation ServicesInformation TechnologySoftware
SeedOct 25, 2022
Amount Raised: $3,300,000
Reema Health

Minneapolis, Minnesota, United States

Reema Health is a technology startup transforming how people navigate the gaps between health care and social care.

Health CareSocialSoftware
SeedMar 30, 2022
Amount Raised: $8,000,000
Koda Health

Houston, Texas, United States

Koda has developed a data-driven, personalized, interactive, video-based platform to navigate difficult conversations in healthcare.

Health CareSoftware
SeedMar 20, 2022
Amount Raised: $3,500,000