IndieBio logo

IndieBio

North America, California, United States, San Francisco

Description

IndieBio, a prominent biotech startup accelerator operated by SOSV, has established itself as a leading force in fostering early-stage deep technology companies. Based in San Francisco, with a strong global reach, IndieBio is dedicated to transforming scientific breakthroughs into viable commercial ventures. Its mission revolves around providing the critical resources, mentorship, and capital necessary for ambitious biotech startups to navigate the complex journey from lab to market, focusing on areas ranging from synthetic biology and therapeutics to sustainable food and biomaterials.

The core of IndieBio's investment model is its intensive accelerator program, which typically provides an initial investment of $500,000 to participating companies. This capital is exchanged for an 8% equity stake, reflecting their commitment to a significant, yet non-dilutive, early-stage partnership. Beyond the financial injection, startups gain unparalleled access to state-of-the-art lab facilities, a vast network of scientific and business mentors, and a structured curriculum designed to accelerate product development and market entry. This comprehensive support system is crucial for deep tech companies that often require substantial infrastructure and specialized expertise.

Since its inception, IndieBio has built an impressive portfolio, having invested in over 200 companies across various biotech sectors. Their rigorous selection process identifies high-potential teams working on groundbreaking science with the potential for significant societal and economic impact. Many of their alumni companies have gone on to raise substantial follow-on funding rounds from top-tier venture capital firms, demonstrating the effectiveness of IndieBio's de-risking and acceleration model. Their strategic approach not only fuels innovation but also helps bridge the funding gap often faced by nascent biotech ventures, positioning them for long-term success in a rapidly evolving industry.

Investor Profile

IndieBio has backed more than 549 startups, with 43 new investments in the last 12 months alone. The firm has led 16 rounds, about 3% of its total and boasts 6 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Seed, Convertible Note, Pre Seed rounds (top funding stages).
  • Majority of deals are located in United States, United Kingdom, Canada.
  • Strong thematic focus on Biotechnology, Health Care, Medical.
  • Typical check size: $500K.

Stage Focus

  • Seed (52%)
  • Convertible Note (24%)
  • Pre Seed (13%)
  • Series A (6%)
  • Series B (2%)
  • Series C (1%)

Country Focus

  • United States (78%)
  • United Kingdom (5%)
  • Canada (5%)
  • Israel (3%)
  • Argentina (2%)
  • Mexico (1%)
  • Ireland (1%)
  • Chile (1%)
  • France (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Medical
  • Food And Beverage
  • Life Science
  • Manufacturing
  • Agriculture
  • Sustainability
  • Therapeutics
  • Health Diagnostics
circle-line
FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does IndieBio frequently co-invest with?

Gaingels
North America, Vermont, United States, Burlington
Co-Investments: 4
KdT Ventures
North America, Texas, United States, Austin
Co-Investments: 4
Sand Hill Angels
North America, California, United States, Mountain View
Co-Investments: 8
SOSV
North America, New Jersey, United States, Princeton
Co-Investments: 519
GRID EXPONENTIAL
South America, Distrito Federal, Argentina, Buenos Aires
Co-Investments: 4
Horizons Ventures
Asia, Hong Kong Island, Hong Kong, Hong Kong
Co-Investments: 4
Cavallo Ventures
North America, California, United States, San Francisco
Co-Investments: 4
GC
North America, New Jersey, United States, Princeton
Co-Investments: 6
Alumni Ventures
North America, New Hampshire, United States, Manchester
Co-Investments: 4
True Ventures
North America, California, United States, Palo Alto
Co-Investments: 6

Which angels does IndieBio often collaborate with?

TF
Europe, Ile-de-France, France, Paris
Shared Deals: 1
JL
North America, Nevada, United States, Las Vegas
Shared Deals: 1
SJ
North America, California, United States, San Francisco
Shared Deals: 2
George Godula
Asia, Shanghai, China, Shanghai
Shared Deals: 1
BG
North America, Washington, United States, Seattle
Shared Deals: 2
FG
North America, California, United States, San Francisco
Shared Deals: 2
MS
North America, California, United States, San Francisco
Shared Deals: 2
RB
North America, California, United States, San Francisco
Shared Deals: 2
NP
North America, California, United States, San Francisco
Shared Deals: 1
KM
North America, Colorado, United States, Denver
Shared Deals: 2

What are some of recent deals done by IndieBio?

Fermeate

San Francisco, California, United States

Fermeate provides photomolecular fermentation technology to increase sustainability and efficiency in the biomanufacturing industry.

BiotechnologyIndustrial ManufacturingSustainability
SeedMar 18, 2025
Capro-X

Ithaca, New York, United States

Capro-X is an ag-tech company that improves the sustainability in the dairy industry.

AgricultureBiotechnologySustainability
SeedMar 14, 2025
Materia Bioworks

Toronto, Ontario, Canada

Materia Bioworks uses cutting-edge technology to enable industry to switch to environmentally friendly alternatives.

BiopharmaBiotechnology
SeedMar 11, 2025
Prellis Biologics

Berkeley, California, United States

Prellis employs holographic tissue printing technology with fully human antibody discovery, in vitro human disease and ADME/Tox models.

3D PrintingBiopharmaBiotechnologyTherapeutics
Series CMar 10, 2025
Puna Bio

Buenos Aires, Distrito Federal, Argentina

Puna Bio develops biological inputs for agriculture that increase yields, reduce carbon emissions, and restore degraded soil.

AgricultureAgTechBiotechnology
Series AMar 6, 2025
Particella

San Francisco, California, United States

Particella develops a novel proprietary lipid nanoparticle that can deliver mRNA and other nucleic acids orally.

BiotechnologyGenetics
Convertible NoteJan 16, 2025
Ten63 Therapeutics

Durham, North Carolina, United States

Ten63 Therapeutics is a venture-backed startup developing durable therapeutics against some of the world’s most lethal diseases.

BiotechnologyHealth CareMedicalPharmaceutical
Series ADec 19, 2024
Farm Minerals

San Francisco, California, United States

Helping farmers to thrive with the most efficient fertilizers and feed additives on the planet.

AgricultureAgTechBiotechnologyManufacturing
SeedDec 19, 2024
Giraffe Bio

Buenos Aires, Distrito Federal, Argentina

Giraffe Bio is a developer of biomolecular technology to improve efficiency and sustainability in critical mineral extraction. The

BiotechnologyMiningMining Technology
SeedDec 19, 2024
AlkaLi Labs

San Francisco, California, United States

AlkaLi Labs is a biotechnology research company that unlocks domestic mineral resources with biological solutions.

BiotechnologyMining
Convertible NoteDec 16, 2024