
National Science Foundation
Description
The National Science Foundation (NSF), through its America’s Seed Fund (SBIR/STTR) program, stands as a pivotal non-dilutive investor for deep technology and science-based startups in the United States. Unlike traditional venture capital firms, NSF's primary mission is to foster the translation of cutting-edge scientific and engineering research into commercial products and services, addressing national needs and promoting economic growth. They target high-risk, high-reward innovations that often struggle to secure early-stage private funding due to their long development cycles or unproven market potential.
NSF's funding mechanism is structured in phases. Phase I awards provide initial seed funding for proof-of-concept and feasibility studies, typically offering up to $275,000 for 6-12 months. Successful Phase I awardees can then apply for Phase II funding, which supports the research and development efforts towards commercialization, with awards typically reaching up to $1,000,000 over 24 months. This phased approach allows companies to de-risk their technology and build a solid foundation without relinquishing equity. The program is substantial, awarding nearly $200 million annually to startups and small businesses, as highlighted by the NSF's own description.
Beyond the significant non-dilutive capital, an NSF award provides substantial validation and prestige, often attracting follow-on private investment from venture capitalists and angel investors who view the rigorous peer-review process as a strong vetting mechanism. Companies also gain access to a network of mentors, business support resources, and government connections, further accelerating their path to market. The NSF's unique position as a government agency focused on foundational research ensures that its investments contribute to the nation's technological leadership and economic competitiveness, making it a highly sought-after funding source for innovative deep tech ventures.
Investor Profile
National Science Foundation has backed more than 4,101 startups, with 51 new investments in the last 12 months alone. The firm has led 3,918 rounds, about 96% of its total and boasts 214 exits across its portfolio.
Investment Focus Highlights
- Concentrates on Grant, Seed, Pre Seed rounds (top funding stages).
- Majority of deals are located in United States, Puerto Rico, United Kingdom.
- Strong thematic focus on Health Care, Biotechnology, Manufacturing.
- Led 47 rounds in the past year.
- Typical check size: $275K – $1M.
Stage Focus
- Grant (99%)
- Seed (1%)
Country Focus
- United States (99%)
Industry Focus
- Health Care
- Biotechnology
- Manufacturing
- Software
- Medical
- Information Technology
- Medical Device
- Education
- Artificial Intelligence (Ai)
- Electronics
Frequently Asked Questions
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