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Signet Healthcare Partners

North America, New York, United States, New York

Description

Signet Healthcare Partners is a New York-based private equity firm with a dedicated focus on the healthcare industry. Established in 1998, the firm specializes in providing growth capital to commercial-stage companies, as well as facilitating recapitalizations and buyouts. Their investment scope spans across various sub-sectors within healthcare, including pharmaceuticals, medical devices, diagnostics, and healthcare services, aiming to partner with management teams to accelerate growth and enhance enterprise value.

The firm's investment thesis is centered on identifying established healthcare businesses that possess proven products or services and are poised for significant expansion. Unlike early-stage venture capital firms, Signet targets companies that have already achieved commercialization, indicating a demonstrated market need and revenue generation. This strategic focus allows them to support companies through critical phases of scaling operations, expanding market reach, and pursuing strategic initiatives such as new product launches or acquisitions.

Signet Healthcare Partners typically deploys substantial capital into its portfolio companies, with a target investment size ranging from $15 million to $50 million per company. This significant check size enables them to be a meaningful partner in growth and provide ample resources for their portfolio companies' strategic objectives. Their commitment to the sector is further evidenced by their recent fundraising success, with their latest fund, Signet Healthcare Partners VI, L.P., closing in 2024 with total commitments of $400 million, underscoring their robust capacity and continued active presence in the healthcare investment landscape.

Investor Profile

Signet Healthcare Partners has backed more than 20 startups, with 2 new investments in the last 12 months alone. The firm has led 11 rounds, about 55% of its total and boasts 8 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series Unknown, Series B, Private Equity rounds (top funding stages).
  • Majority of deals are located in United States, Germany, Norway.
  • Strong thematic focus on Biotechnology, Pharmaceutical, Health Care.
  • Led 1 rounds in the past year.
  • Typical check size: $15M – $50M.

Stage Focus

  • Series Unknown (30%)
  • Series B (20%)
  • Private Equity (20%)
  • Series C (15%)
  • Series D (10%)
  • Series A (5%)

Country Focus

  • United States (60%)
  • Germany (15%)
  • Norway (5%)
  • Australia (5%)
  • The Netherlands (5%)
  • Switzerland (5%)
  • Sweden (5%)

Industry Focus

  • Biotechnology
  • Pharmaceutical
  • Health Care
  • Manufacturing
  • Medical
  • Medical Device
  • Life Science
  • Clinical Trials
  • Emergency Medicine
  • Retail
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Signet Healthcare Partners frequently co-invest with?

TVM Capital
Europe, Bayern, Germany, Munich
Co-Investments: 2
Cane Investment Partners
North America, Illinois, United States, Chicago
Co-Investments: 1
Athyrium Capital Management LP
North America, New York, United States, New York
Co-Investments: 1
TVM Capital Life Science
Europe, Bayern, Germany, Munich
Co-Investments: 2
C
Europe, Baden-Wurttemberg, Germany, Heidelberg
Co-Investments: 2
AH
North America, Delaware, United States, Dover
Co-Investments: 1
Pharmascience
North America, Quebec, Canada, Montréal
Co-Investments: 2
JW Asset Management
North America, New York, United States, New York
Co-Investments: 1
AC
Oceania, New South Wales, Australia, Sydney
Co-Investments: 2
Hildred Capital Partners
North America, New York, United States, New York
Co-Investments: 1

What are some of recent deals done by Signet Healthcare Partners?

NorthX Biologics

Matfors, Vasternorrlands Lan, Sweden

NorthX Biologics offer services and support in the development and manufacturing of biologics.

Private EquityMay 14, 2025
leon nanodrugs

München, Bayern, Germany

leon-nanodrugs is a nanotechnology-based drug development company.

BiotechnologyHealth CareMedicalPharmaceutical
Series DAug 6, 2024
Curida

Elverum, Hedmark, Norway

Curida is a pharmaceutical contract development and manufacturing organization (CDMO) with core competence on Blow-Fill-Seal.

BiotechnologyManufacturingPharmaceutical
Private EquityApr 15, 2024
Paragonix Technologies

Cambridge, Massachusetts, United States

Paragonix Technologies is a medical device company specialized in organ preservation devices for the improvement of donor organ quality.

BiotechnologyHealth CareMedical Device
Series BMar 7, 2023
Amount Raised: $24,000,000
Juno Pharmaceuticals

Cremorne, New South Wales, Australia

Juno Pharmaceuticals produces and distributes amoxicillin, hydrochloride syringes, hydromorphone solutions, phentermine tablets & capsules.

ManufacturingMedicalMedical DevicePharmaceuticalRetail
Private EquityFeb 24, 2022
Ascendia Pharmaceuticals

North Brunswick, New Jersey, United States

Ascendia Pharmaceuticals offers a comprehensive suite of pre-formulation for preclinical- and clinical-stage drug candidates.

BiotechnologyHealth CarePharmaceutical
Series UnknownApr 8, 2021
Leading Pharma

Fairfield, New Jersey, United States

A Airfield, NJ based generic pharmaceutical company .

Emergency MedicineHealth CareManufacturingPharmaceutical
Series UnknownJan 8, 2018
Amount Raised: $40,000,000
TELA Bio

Malvern, Pennsylvania, United States

TELA Bio is a life science company that specializes in soft tissue reconstruction.

BiotechnologyLife SciencePharmaceutical
Series UnknownOct 30, 2017
Amount Raised: $25,000,000
Pharmaceutics International

Hunt Valley, Maryland, United States

Pharmaceutics International operates as a science-driven contract development and manufacturing company.

Clinical TrialsHealth CareManufacturingPharmaceutical
Private EquitySep 6, 2016
Amount Raised: $93,000,000
leon nanodrugs

München, Bayern, Germany

leon-nanodrugs is a nanotechnology-based drug development company.

BiotechnologyHealth CareMedicalPharmaceutical
Series AJul 27, 2015
Amount Raised: $20,513,571