The Leona M. and Harry B. Helmsley Charitable Trust logo

The Leona M. and Harry B. Helmsley Charitable Trust

North America, South Dakota, United States, Sioux Falls

Description

The Helmsley Charitable Trust aspires to improve lives by supporting exceptional efforts in the U.S.

Investor Profile

The Leona M. and Harry B. Helmsley Charitable Trust has backed more than 18 startups, with 2 new investments in the last 12 months alone. The firm has led 18 rounds, about 100% of its total and boasts 2 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Grant, Debt Financing rounds (top funding stages).
  • Majority of deals are located in United States, Israel, Canada.
  • Strong thematic focus on Health Care, Biotechnology, Medical.
  • Led 2 rounds in the past year.

Stage Focus

  • Grant (83%)
  • Debt Financing (17%)

Country Focus

  • United States (83%)
  • Israel (11%)
  • Canada (6%)

Industry Focus

  • Health Care
  • Biotechnology
  • Medical
  • Non Profit
  • Pharmaceutical
  • Medical Device
  • Genetics
  • Hospital
  • Diabetes
  • Clinical Trials
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does The Leona M. and Harry B. Helmsley Charitable Trust frequently co-invest with?

JDRF (The Juvenile Diabetes Research Foundation)
North America, New York, United States, New York
Co-Investments: 1

What are some of recent deals done by The Leona M. and Harry B. Helmsley Charitable Trust?

Alliance of Community Health Plan

Washington, District of Columbia, United States

A new infographic from the Alliance of Community Health Plans highlights rising.

AssociationCommunitiesFitnessHealth CareNon Profit
GrantOct 9, 2025
Amount Raised: $4,200,000
Genetic Alliance

Washington, District of Columbia, United States

Genetic Alliance is a non-profit organization that focuses on health advocacy and the rapid advancement of genetic technology.

BiotechnologyHealth CareNon Profit
GrantJul 15, 2025
Amount Raised: $500,000
Thetis Pharmaceuticals

Ridgefield, Connecticut, United States

Thetis Pharmaceuticals is a biopharmaceutical company.

BiotechnologyClinical TrialsMedicalPharmaceutical
Debt FinancingJan 9, 2025
Amount Raised: $8,975,000
TIXiMED

Birmingham, Alabama, United States

TIXiMED is a biotechnology company that develops and commercialises medicines for diabetes treatment.

BiopharmaBiotechnologyHealth CareMedical
Debt FinancingDec 19, 2024
Amount Raised: $2,650,000
Icahn School of Medicine at Mount Sinai

New York, New York, United States

Icahn School of Medicine at Mount Sinai is a medical school located in New York.

GeneticsHealth CareMedical
GrantJan 25, 2024
Amount Raised: $4,000,000
NYC Health + Hospitals

New York, New York, United States

NYC Health + Hospitals is an interconnected system of hospitals, health care centers, nursing homes, and home care.

Health Care
GrantAug 4, 2022
Amount Raised: $3,900,000
Brigham and Women's Hospital

Boston, Massachusetts, United States

Brigham and Women's Hospital is an academic medical center based in Boston, Massachusetts.

Health CareMedical
GrantJun 30, 2022
Amount Raised: $16,000,000
Thetis Pharmaceuticals

Ridgefield, Connecticut, United States

Thetis Pharmaceuticals is a biopharmaceutical company.

BiotechnologyClinical TrialsMedicalPharmaceutical
GrantApr 5, 2022
Amount Raised: $4,200,000
Shamir Medical Centre

Tel Aviv, Tel Aviv, Israel

Shamir Medical Center provides medical care and services to the community.

CommunitiesHealth CareMedical
GrantNov 18, 2021
Amount Raised: $8,800,000
Beyond Type 1

San Mateo, California, United States

Beyond Type 1 is the largest diabetes org online, funding advocacy, education and cure research.

Health CareNon Profit
GrantNov 9, 2021
Amount Raised: $750,000

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