
Vertex Ventures HC
Description
Vertex Ventures HC is a dedicated healthcare venture capital fund based in Palo Alto, United States, specializing in early-stage and growth-stage investments across the biopharmaceutical, medical device, and digital health sectors. As part of the broader Vertex Holdings global network, the firm leverages an extensive international presence and deep industry expertise to identify and nurture transformative healthcare companies. Their strategic focus is on innovative solutions that address significant unmet medical needs and improve patient outcomes.
The firm's investment strategy centers on providing capital and strategic support to companies from Series A through Series C rounds. Vertex Ventures HC is known for its hands-on approach, working closely with portfolio companies to accelerate their development, navigate regulatory pathways, and scale their operations. A significant milestone for the firm was the closing of its second fund, Vertex Ventures HC Fund II, in 2021, which secured $200 million in commitments. This followed their successful first fund, Vertex Ventures HC Fund I, which closed at $150 million in 2018, demonstrating their growing capacity and commitment to the healthcare innovation ecosystem.
While specific check sizes can vary depending on the stage and needs of the portfolio company, Vertex Ventures HC typically deploys initial investments ranging from $5 million to $20 million. This range allows them to lead or co-lead Series A rounds, where they often provide significant capital and strategic guidance, as well as participate meaningfully in larger Series B and C rounds. The firm seeks out companies with strong scientific foundations, experienced management teams, and clear pathways to market, aiming to build long-term partnerships that drive substantial value creation in the healthcare industry.
Investor Profile
Vertex Ventures HC has backed more than 42 startups, with 4 new investments in the last 12 months alone. The firm has led 3 rounds, about 7% of its total and boasts 9 exits across its portfolio.
Investment Focus Highlights
- Concentrates on Series B, Series C, Series A rounds (top funding stages).
- Majority of deals are located in United States, United Kingdom, Switzerland.
- Strong thematic focus on Biotechnology, Health Care, Medical.
- Typical check size: $5M – $20M.
Stage Focus
- Series B (31%)
- Series C (24%)
- Series A (24%)
- Series D (14%)
- Series E (2%)
- Debt Financing (2%)
- Series Unknown (2%)
Country Focus
- United States (93%)
- United Kingdom (2%)
- Switzerland (2%)
- China (2%)
Industry Focus
- Biotechnology
- Health Care
- Medical
- Therapeutics
- Medical Device
- Pharmaceutical
- Biopharma
- Life Science
- Clinical Trials
- Oncology
Frequently Asked Questions
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