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Vertex Ventures US

North America, California, United States, Palo Alto

Description

Vertex Ventures US is a prominent early-stage venture capital firm based in Palo Alto, California, specializing in investments in B2B software and infrastructure companies. As part of the global Vertex Ventures network, which is backed by Temasek Holdings, the firm leverages a deep understanding of enterprise technology and a founder-first approach. They primarily target Seed and Series A rounds, aiming to partner with visionary entrepreneurs building foundational technologies for the modern business landscape.

The firm's investment strategy is characterized by leading early-stage rounds, providing substantial capital to help companies scale from inception. Vertex Ventures US typically invests between $5 million and $15 million in their initial checks, positioning themselves as a significant partner for nascent B2B ventures. Their focus extends to areas such as developer tools, cybersecurity, cloud infrastructure, data platforms, and AI/ML applications, reflecting a keen eye on emerging technological shifts that impact enterprise operations.

Beyond capital, Vertex Ventures US offers a robust support system, including operational guidance, strategic advice, and access to a vast network of industry experts, potential customers, and follow-on investors. The firm closed its fourth fund, Vertex Ventures US Fund IV, at $200 million in March 2021, demonstrating continued commitment and capacity to support a new generation of B2B innovators. This capital base, combined with their hands-on engagement, helps portfolio companies navigate critical growth stages, from product-market fit to market expansion. Their global network affiliation also provides unique cross-border opportunities and insights for their portfolio companies.

Investor Profile

Vertex Ventures US has backed more than 63 startups, with 8 new investments in the last 12 months alone. The firm has led 22 rounds, about 35% of its total and boasts 10 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Seed, Series A, Series B rounds (top funding stages).
  • Majority of deals are located in United States, United Kingdom, Germany.
  • Strong thematic focus on Software, Artificial Intelligence (AI), Information Technology.
  • Led 2 rounds in the past year.
  • Typical check size: $5M – $15M.

Stage Focus

  • Seed (40%)
  • Series A (30%)
  • Series B (16%)
  • Series C (10%)
  • Series D (2%)
  • Series Unknown (2%)
  • Pre Seed (2%)

Country Focus

  • United States (81%)
  • United Kingdom (6%)
  • Germany (5%)
  • Canada (3%)
  • Kenya (2%)
  • India (2%)
  • Switzerland (2%)

Industry Focus

  • Software
  • Artificial Intelligence (Ai)
  • Information Technology
  • Saas
  • Analytics
  • Security
  • Developer Tools
  • Machine Learning
  • Big Data
  • Network Security
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Vertex Ventures US frequently co-invest with?

Seedcamp
Europe, England, United Kingdom, London
Co-Investments: 4
Wing Venture Capital
North America, California, United States, Palo Alto
Co-Investments: 5
Crane Venture Partners
Europe, England, United Kingdom, London
Co-Investments: 3
Foundation Capital
North America, California, United States, Palo Alto
Co-Investments: 3
Battery Ventures
North America, Massachusetts, United States, Boston
Co-Investments: 3
Vertex Ventures
Asia, Central Region, Singapore, Singapore
Co-Investments: 26
Lux Capital
North America, New York, United States, New York
Co-Investments: 3
Costanoa Ventures
North America, California, United States, Palo Alto
Co-Investments: 3
Village Global
North America, California, United States, Covina
Co-Investments: 3
DCVC
North America, California, United States, San Francisco
Co-Investments: 3

Which angels does Vertex Ventures US often collaborate with?

Ariel Maislos
Asia, Israel
Shared Deals: 2
JR
North America, California, United States, San Francisco
Shared Deals: 2
AS
North America, California, United States, San Francisco
Shared Deals: 1
KS
North America, California, United States
Shared Deals: 1
Dan Scheinman
North America, California, United States, San Francisco
Shared Deals: 2
AA
North America, California, United States, San Francisco
Shared Deals: 1
CF
North America, Illinois, United States, Chicago
Shared Deals: 1
AC
North America, California, United States
Shared Deals: 1
Shu Duan
Asia, Hong Kong Island, Hong Kong, Hong Kong
Shared Deals: 1
BH
Europe, England, United Kingdom, London
Shared Deals: 2

What are some of recent deals done by Vertex Ventures US?

Metaview

London, England, United Kingdom

The AI Platform for Recruiting Conversations

Artificial Intelligence (AI)Human ResourcesRecruiting
Series BJun 25, 2025
Amount Raised: $34,990,195
SWARM Biotactics

Kassel, Hessen, Germany

SWARM Biotactics develops bio-robotic systems based on fully controllable living insects for mission-critical activities.

Artificial Intelligence (AI)Robotics
SeedJun 24, 2025
Amount Raised: $11,597,955
Cakewalk

Berlin, Berlin, Germany

Easy and Powerful Identity Governance for Buys IT and InfoSec Teams.

ComplianceIT ManagementSecurity
SeedApr 23, 2025
Amount Raised: $7,500,000
Recce

San Francisco, California, United States

Solving the data context problem

Cloud Data ServicesDeveloper ToolsOpen Source
Pre SeedApr 22, 2025
Amount Raised: $4,000,000
Rad Security

San Francisco, California, United States

The Future of Security: AI-Driven, Real-Time Defense

Event ManagementInformation TechnologyIT InfrastructureSaaS
Series AFeb 24, 2025
Amount Raised: $14,000,000
Riley AI

San Francisco, California, United States

Riley AI is an AI-powered platform that specializes in automated data analysis and streamlined collaboration services.

Artificial Intelligence (AI)Information TechnologySoftware
SeedJan 23, 2025
Amount Raised: $3,000,000
Northflank

London, England, United Kingdom

Northflank is a developer platform that automates deployments across cloud infrastructures.

Cloud ManagementSoftwareWeb Development
SeedNov 11, 2024
Amount Raised: $6,300,000
HUMAN

New York, New York, United States

HUMAN is a cybersecurity company that protects the internet and enterprises from fraud and sophisticated bot attacks.

AdvertisingArtificial Intelligence (AI)Cyber SecurityFraud DetectionInternetSecuritySoftware
Series UnknownOct 9, 2024
Amount Raised: $50,000,000
Metaview

London, England, United Kingdom

The Recruiting Assistance Platform

AnalyticsHuman ResourcesRecruitingSpeech Recognition
Series AMar 28, 2024
Amount Raised: $7,000,000
Orkes

Cupertino, California, United States

Orkes is a microservices and workflow orchestration platform.

AppsArtificial Intelligence (AI)Cloud ComputingOpen Source
Series AFeb 21, 2024
Amount Raised: $20,000,000