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Amplitude Venture Capital

North America, Quebec, Canada, Montréal

Description

Amplitude Venture Capital is a prominent Canadian venture capital firm based in Montréal, dedicated to building and investing in the next generation of life science companies. Established with a clear focus on transforming scientific innovation into commercial success, Amplitude targets opportunities from inception through to commercialization. The firm leverages a deep understanding of the life sciences sector, aiming to address significant unmet medical needs through novel platforms and therapies. Their investment thesis emphasizes the creation of robust, globally competitive companies within Canada's burgeoning biotech ecosystem.

The firm's investment strategy is characterized by its hands-on approach and commitment to leading significant funding rounds. Amplitude typically leads Series A and Series B rounds, providing substantial capital to fuel the development and growth of its portfolio companies. Initial investments from Amplitude Venture Capital generally range from C$5 million to C$15 million, which translates to approximately $3.65 million to $10.95 million USD based on current exchange rates. This considerable check size allows them to support ambitious projects that require significant capital for research, development, and clinical trials.

Amplitude has demonstrated strong fundraising capabilities, having successfully closed two major funds. Their first fund, launched in 2020, secured C$200 million, while their second fund, announced in 2023, raised an impressive C$300 million. Collectively, these funds provide Amplitude with over C$500 million in committed capital, solidifying its position as a major player in the Canadian life sciences venture landscape. Beyond capital, Amplitude offers strategic guidance, operational support, and access to an extensive network of industry experts, aiming to accelerate the journey of its portfolio companies from scientific discovery to market leadership.

Investor Profile

Amplitude Venture Capital has backed more than 25 startups, with 5 new investments in the last 12 months alone. The firm has led 11 rounds, about 44% of its total and boasts 5 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series A, Seed rounds (top funding stages).
  • Majority of deals are located in Canada, United States, Israel.
  • Strong thematic focus on Biotechnology, Health Care, Life Science.
  • Led 3 rounds in the past year.
  • Typical check size: $3.6M – $10.9M.

Stage Focus

  • Series B (32%)
  • Series A (32%)
  • Seed (28%)
  • Series C (8%)

Country Focus

  • Canada (80%)
  • United States (16%)
  • Israel (4%)

Industry Focus

  • Biotechnology
  • Health Care
  • Life Science
  • Therapeutics
  • Medical
  • Pharmaceutical
  • Genetics
  • Artificial Intelligence (Ai)
  • Oncology
  • Health Diagnostics
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Amplitude Venture Capital frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 3
Fonds de solidarité FTQ
North America, Quebec, Canada, Montréal
Co-Investments: 7
Amgen Ventures
North America, California, United States, San Francisco
Co-Investments: 2
Alexandria Venture Investments
North America, California, United States, Pasadena
Co-Investments: 6
Casdin Capital
North America, New York, United States, New York
Co-Investments: 2
Versant Ventures
North America, California, United States, Menlo Park
Co-Investments: 4
Lumira Ventures
North America, Ontario, Canada, Toronto
Co-Investments: 3
Theodorus III
Europe, Brussels Hoofdstedelijk Gewest, Belgium, Brussels
Co-Investments: 3
Charles River Laboratories International
North America, Massachusetts, United States, Wilmington
Co-Investments: 2
Investissement Quebec
North America, Quebec, Canada, Quebec
Co-Investments: 3

Which angels does Amplitude Venture Capital often collaborate with?

Clarissa Desjardins
North America, Quebec, Canada, Montréal
Shared Deals: 1
JM
North America, Massachusetts, United States, Cambridge
Shared Deals: 1

What are some of recent deals done by Amplitude Venture Capital?

Reverb Therapeutics

Vancouver, British Columbia, Canada

Reverb Therapeutics engages in the development of treatments for cancer and other diseases.

Health CareMedicalTherapeutics
SeedFeb 19, 2025
Amount Raised: $12,000,000
Fluid Biomed

Calgary, Alberta, Canada

Fluid Biomed is a clinical stage medical device company that develops polymer-based brain stent to cure aneurysms.

Health CareMedicalMedical Device
Series ADec 16, 2024
Amount Raised: $27,000,000
Evommune

Palo Alto, California, United States

Evommune is a biotechnology company that develops therapeutics that halt progressive disease and address their symptoms.

BiotechnologyHealth CareLife Science
Series COct 31, 2024
Amount Raised: $115,000,000
Nomic

Montréal, Quebec, Canada

Nomic develops a proteomic technology platform to understand, detect, and treat diseases with DNA nanotechnology.

BiotechnologyHealth DiagnosticsMarket ResearchNanotechnology
Series BSep 17, 2024
Amount Raised: $42,000,000
Radiant Biotherapeutics

Toronto, Ontario, Canada

Radiant is a biotechnology company developing the next generation of multi-specificity.

BiotechnologyTherapeutics
Series ASep 11, 2024
Amount Raised: $35,000,000
Ability biologics

Ville-marie, Quebec, Canada

Ability Biologics dedicated to developing the most potent and selective antibody therapeutics for areas of great unmet need..

BiotechnologyLife Science
SeedJun 18, 2024
Amount Raised: $6,000,000
Ability biologics

Ville-marie, Quebec, Canada

Ability Biologics dedicated to developing the most potent and selective antibody therapeutics for areas of great unmet need..

BiotechnologyLife Science
SeedDec 6, 2023
Amount Raised: $12,000,000
Reverb Therapeutics

Vancouver, British Columbia, Canada

Reverb Therapeutics engages in the development of treatments for cancer and other diseases.

Health CareMedical
SeedNov 15, 2023
Tentarix Biotherapeutics

San Diego, California, United States

Tentarix creates innovative protein therapeutics with uniquely combined bioactivities that leverage synthetic biology.

BiotechnologyLife ScienceMedical
Series BSep 6, 2023
Amount Raised: $35,000,000
Evommune

Palo Alto, California, United States

Evommune is a biotechnology company that develops therapeutics that halt progressive disease and address their symptoms.

BiotechnologyHealth CareLife Science
Series BApr 26, 2023
Amount Raised: $50,000,000