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OrbiMed

North America, New York, United States, New York

Description

OrbiMed is a preeminent global investment firm exclusively dedicated to the healthcare sector, headquartered in New York City. Established with a singular focus on healthcare, the firm employs a comprehensive investment strategy that spans the entire industry, from early-stage venture capital to growth equity, public equity, and credit investments. This broad mandate allows OrbiMed to support companies at virtually every stage of their lifecycle, fostering innovation and growth across biopharmaceuticals, medical devices, diagnostics, and digital health solutions worldwide. Their deep industry expertise and extensive network are central to their value proposition, enabling them to identify and nurture promising healthcare ventures.

The firm's investment approach is characterized by its long-term perspective and a commitment to partnering with management teams to build successful enterprises. OrbiMed's global presence, with offices in major financial and biotech hubs, facilitates a diverse portfolio that reflects the dynamic nature of the healthcare landscape. As of early 2024, OrbiMed manages approximately $18 billion in assets, underscoring its significant financial capacity and influence within the healthcare investment ecosystem. This substantial capital base allows them to deploy considerable resources into both emerging and established companies, driving significant advancements in patient care and medical technology.

OrbiMed's typical first cheque sizes are reflective of its multi-stage investment strategy and the substantial capital it manages. While they participate in seed and early-stage venture rounds, their significant private equity funds enable larger commitments. For instance, in 2022, the firm closed its OrbiMed Private Investments IX fund with $4.3 billion in capital commitments, demonstrating their capacity for substantial investments. Consequently, a typical first cheque for a private company can range widely, often starting from around $10 million for early-stage venture deals and extending up to $200 million or more for growth equity or later-stage private investments, particularly when taking a lead or significant co-lead position in a funding round. This flexibility allows them to tailor their investment to the specific needs and stage of the target company, from innovative startups to established market leaders.

Investor Profile

OrbiMed has backed more than 693 startups, with 39 new investments in the last 12 months alone. The firm has led 231 rounds, about 33% of its total and boasts 252 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series A, Series C rounds (top funding stages).
  • Majority of deals are located in United States, China, Israel.
  • Strong thematic focus on Biotechnology, Health Care, Medical.
  • Led 10 rounds in the past year.
  • Typical check size: $10M – $200M.

Stage Focus

  • Series B (23%)
  • Series A (19%)
  • Series C (17%)
  • Post Ipo Equity (12%)
  • Series Unknown (11%)
  • Series D (7%)
  • Series E (3%)
  • Series F (2%)
  • Post Ipo Debt (2%)
  • Private Equity (2%)

Country Focus

  • United States (71%)
  • China (8%)
  • Israel (7%)
  • Canada (3%)
  • United Kingdom (3%)
  • India (2%)
  • Switzerland (2%)
  • France (2%)
  • Germany (1%)
  • Denmark (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Medical
  • Pharmaceutical
  • Therapeutics
  • Biopharma
  • Medical Device
  • Life Science
  • Health Diagnostics
  • Oncology
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does OrbiMed frequently co-invest with?

HBM Healthcare Investments
Europe, Zug, Switzerland, Zug
Co-Investments: 30
Surveyor Capital
North America, Illinois, United States, Chicago
Co-Investments: 35
CA
North America, Massachusetts, United States, Boston
Co-Investments: 41
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 71
Novo Holdings
Europe, Hovedstaden, Denmark, Hellerup
Co-Investments: 31
Foresite Capital
North America, California, United States, San Francisco
Co-Investments: 35
Vivo Capital
North America, California, United States, Palo Alto
Co-Investments: 37
Logos Capital
North America, California, United States, San Francisco
Co-Investments: 33
Lilly Asia Ventures
Asia, Shanghai, China, Shanghai
Co-Investments: 35
Fidelity
North America, Massachusetts, United States, Boston
Co-Investments: 31

Which angels does OrbiMed often collaborate with?

RA
North America, United States
Shared Deals: 1
ME
Europe, England, United Kingdom
Shared Deals: 1
PT
North America, California, United States, San Francisco
Shared Deals: 3
AU
Europe, Hallands Lan, Sweden, Kungsbacka
Shared Deals: 1
Mark W. Hahn
North America, North Carolina, United States, Chapel Hill
Shared Deals: 1
Zohar Zisapel
Asia, Tel Aviv, Israel, Tel Aviv
Shared Deals: 2
VS
North America, Massachusetts, United States, Boston
Shared Deals: 1
LB
North America, Massachusetts, United States, Cambridge
Shared Deals: 2
David Zaccardelli
North America, United States
Shared Deals: 1
DE
Europe, Zurich, Switzerland, Zürich
Shared Deals: 1

What are some of recent deals done by OrbiMed?

Pinnacle Medicines

Doylestown, Pennsylvania, United States

Pinnacle Medicines is a peptide drug discovery company that provides peptide modality for medical needs.

BiopharmaBiotechnologyMedical
Series BMar 26, 2026
Amount Raised: $89,000,000
Congruence Therapeutics

Montréal, Quebec, Canada

Congruence Therapeutics operates as a biotechnology company.

BiotechnologyMedical
Series UnknownMar 19, 2026
Amount Raised: $39,500,000
Stairway Medical

Pudong, Shandong, China

Stairway Medical is a developer of implantable brain-computer interface technology.

Health CareMedicalMedical DeviceNeuroscience
Series UnknownMar 13, 2026
Amount Raised: $72,623,751
Relmada Therapeutics

New York, New York, United States

Relmada Therapeutics is a biotech company addressing diseases of the central nervous system, with a focus on major depressive disorder.

BiotechnologyClinical TrialsPharmaceutical
Post Ipo EquityMar 9, 2026
Amount Raised: $160,000,000
Shenluo Medical

Hangzhou, Zhejiang, China

Shenluo Medical manufactures functional neural implantable medical devices.

Health CareManufacturing
Series CMar 4, 2026
QL Biopharma

Changping, Beijing, China

QL Biopharma focuses on developing innovative drugs and premium me-too drugs targeting metabolic diseases.

BiopharmaHealth CareMedical
Series CMar 2, 2026
Amount Raised: $72,780,204
Immunic Therapeutics

New York, New York, United States

Immunic is a biopharmaceutical company that develops a pipeline of selective oral immunology therapies.

BiotechnologyLife ScienceMedicalTherapeutics
Post Ipo EquityFeb 13, 2026
Amount Raised: $400,000,000
Xilio Therapeutics

Waltham, Massachusetts, United States

Xilio Therapeutics is a biotechnology company that develops tumor-activated immuno-oncology therapies.

BiopharmaBiotechnologyHealth CareOncologyTherapeutics
Post Ipo EquityFeb 11, 2026
Amount Raised: $40,000,000
Angitia Biopharmaceuticals

Westlake Village, California, United States

Angitia Biopharmaceuticals develops biologic therapies for musculoskeletal diseases.

BiopharmaBiotechnologyHealth CareMedical
Series DFeb 5, 2026
Amount Raised: $130,000,000
Mendra

San Francisco, California, United States

Mendra uses AI to accelerate clinical development and commercialization of breakthrough medicines for diseases with high unmet need.

Artificial Intelligence (AI)BiopharmaMedical
Series AJan 21, 2026
Amount Raised: $82,000,000

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