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OrbiMed

North America, New York, United States, New York

Description

OrbiMed is a preeminent global investment firm exclusively dedicated to the healthcare sector, headquartered in New York City. Established with a singular focus on healthcare, the firm employs a comprehensive investment strategy that spans the entire industry, from early-stage venture capital to growth equity, public equity, and credit investments. This broad mandate allows OrbiMed to support companies at virtually every stage of their lifecycle, fostering innovation and growth across biopharmaceuticals, medical devices, diagnostics, and digital health solutions worldwide. Their deep industry expertise and extensive network are central to their value proposition, enabling them to identify and nurture promising healthcare ventures.

The firm's investment approach is characterized by its long-term perspective and a commitment to partnering with management teams to build successful enterprises. OrbiMed's global presence, with offices in major financial and biotech hubs, facilitates a diverse portfolio that reflects the dynamic nature of the healthcare landscape. As of early 2024, OrbiMed manages approximately $18 billion in assets, underscoring its significant financial capacity and influence within the healthcare investment ecosystem. This substantial capital base allows them to deploy considerable resources into both emerging and established companies, driving significant advancements in patient care and medical technology.

OrbiMed's typical first cheque sizes are reflective of its multi-stage investment strategy and the substantial capital it manages. While they participate in seed and early-stage venture rounds, their significant private equity funds enable larger commitments. For instance, in 2022, the firm closed its OrbiMed Private Investments IX fund with $4.3 billion in capital commitments, demonstrating their capacity for substantial investments. Consequently, a typical first cheque for a private company can range widely, often starting from around $10 million for early-stage venture deals and extending up to $200 million or more for growth equity or later-stage private investments, particularly when taking a lead or significant co-lead position in a funding round. This flexibility allows them to tailor their investment to the specific needs and stage of the target company, from innovative startups to established market leaders.

Investor Profile

OrbiMed has backed more than 693 startups, with 39 new investments in the last 12 months alone. The firm has led 231 rounds, about 33% of its total and boasts 252 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series A, Series C rounds (top funding stages).
  • Majority of deals are located in United States, China, Israel.
  • Strong thematic focus on Biotechnology, Health Care, Medical.
  • Led 10 rounds in the past year.
  • Typical check size: $10M – $200M.

Stage Focus

  • Series B (23%)
  • Series A (19%)
  • Series C (17%)
  • Post Ipo Equity (12%)
  • Series Unknown (11%)
  • Series D (7%)
  • Series E (3%)
  • Series F (2%)
  • Post Ipo Debt (2%)
  • Private Equity (2%)

Country Focus

  • United States (71%)
  • China (8%)
  • Israel (7%)
  • Canada (3%)
  • United Kingdom (3%)
  • India (2%)
  • Switzerland (2%)
  • France (2%)
  • Germany (1%)
  • Denmark (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Medical
  • Pharmaceutical
  • Therapeutics
  • Biopharma
  • Medical Device
  • Life Science
  • Health Diagnostics
  • Oncology
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does OrbiMed frequently co-invest with?

HBM Healthcare Investments
Europe, Zug, Switzerland, Zug
Co-Investments: 30
Surveyor Capital
North America, Illinois, United States, Chicago
Co-Investments: 35
CA
North America, Massachusetts, United States, Boston
Co-Investments: 41
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 71
Novo Holdings
Europe, Hovedstaden, Denmark, Hellerup
Co-Investments: 31
Foresite Capital
North America, California, United States, San Francisco
Co-Investments: 35
Vivo Capital
North America, California, United States, Palo Alto
Co-Investments: 37
Logos Capital
North America, California, United States, San Francisco
Co-Investments: 33
Lilly Asia Ventures
Asia, Shanghai, China, Shanghai
Co-Investments: 35
Fidelity
North America, Massachusetts, United States, Boston
Co-Investments: 31

Which angels does OrbiMed often collaborate with?

RA
North America, United States
Shared Deals: 1
ME
Europe, England, United Kingdom
Shared Deals: 1
PT
North America, California, United States, San Francisco
Shared Deals: 3
AU
Europe, Hallands Lan, Sweden, Kungsbacka
Shared Deals: 1
Mark W. Hahn
North America, North Carolina, United States, Chapel Hill
Shared Deals: 1
Zohar Zisapel
Asia, Tel Aviv, Israel, Tel Aviv
Shared Deals: 2
VS
North America, Massachusetts, United States, Boston
Shared Deals: 1
LB
North America, Massachusetts, United States, Cambridge
Shared Deals: 2
David Zaccardelli
North America, United States
Shared Deals: 1
DE
Europe, Zurich, Switzerland, Zürich
Shared Deals: 1

What are some of recent deals done by OrbiMed?

Mendra

San Francisco, California, United States

Mendra uses AI to accelerate clinical development and commercialization of breakthrough medicines for diseases with high unmet need.

Artificial Intelligence (AI)BiopharmaMedical
Series AJan 21, 2026
Amount Raised: $82,000,000
Pee Safe

Gurgaon, Haryana, India

Started in 2013, Redcliffe Hygiene Private Limited is India's fastest growing hygiene company.

Consumer GoodsFast-Moving Consumer GoodsFitnessHealth CareWellness
Series CJan 14, 2026
Amount Raised: $32,000,000
Mirador Therapeutics

San Diego, California, United States

Mirador Therapeutics develops precision medicines for immune-mediated diseases.

BiotechnologyHealth CareMedicalTherapeutics
Series BJan 12, 2026
Amount Raised: $250,000,000
AirNexis Therapeutics

Palo Alto, California, United States

AirNexis Therapeutics develops clinical-stage therapies for chronic obstructive pulmonary disease and other pulmonary conditions.

BiotechnologyHealth CareTherapeutics
Series AJan 9, 2026
Amount Raised: $200,000,000
Biobeat

Boca Raton, Florida, United States

Biobeat is a med-tech company that develops remote patient monitoring and data collection tool.

BiotechnologyData Collection and LabelingHealth CareMedical DeviceWearables
Series BDec 30, 2025
Amount Raised: $50,000,000
Yarrow

New York, New York, United States

Yarrow is developing a first-in-class antibody targeting TSHR for the treatment of Graves’ disease and thyroid eye disease.

Business IntelligenceHealth CareMedical
Series UnknownDec 17, 2025
Amount Raised: $200,000,000
ProLynx

San Francisco, California, United States

ProLynx is a biotechnology company that develops proprietary drug-delivery technologies to extend the half-life of therapeutic molecules.

BiotechnologyHealth CareManufacturingTherapeutics
Series ADec 11, 2025
Amount Raised: $70,000,000
BlossomHill Therapeutics

San Diego, California, United States

BlossomHill Therapeutics is a biopharmaceutical company focusing on oncology and autoimmune disorders.

BiopharmaBiotechnologyHealth CareOncologyPharmaceuticalTherapeutics
Series BDec 10, 2025
Amount Raised: $84,000,000
Proviva Therapeutics

Shanghai, Shanghai, China

Proviva Therapeutics is a pro-drug design platform for cytokines and other fusion proteins.

BiotechnologyLife ScienceMedicalTherapeutics
Series ADec 1, 2025
Amount Raised: $30,000,000
Aspen Neuroscience

San Diego, California, United States

Aspen Neuroscience is a biotechnology company that specializes in personalized cell therapies and autologous regenerative medicine.

BiotechnologyMedicalNeurosciencePharmaceuticalTherapeutics
Series CNov 20, 2025
Amount Raised: $115,000,000

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