Foresite Capital logo

Foresite Capital

North America, California, United States, San Francisco

Description

Foresite Capital is a prominent multi-stage healthcare and life sciences investment firm based in San Francisco, United States. With approximately $10 billion in assets under management (AUM), the firm is a significant player in the biotech and health tech sectors. Foresite Capital's investment thesis centers on identifying and supporting innovative companies across therapeutics, life science tools, diagnostics, and digital health, aiming to drive advancements that address critical unmet medical needs.

The firm employs a flexible investment strategy, engaging with companies from their earliest stages of formation through to public market listings. While they participate across the entire lifecycle, Foresite Capital is particularly known for leading substantial growth equity rounds. Their typical first cheque for a significant investment generally ranges from $20 million to $100 million, reflecting their commitment to providing substantial capital to fuel company growth and development. This multi-stage approach allows them to build long-term relationships with portfolio companies, offering strategic guidance and operational support alongside financial backing.

Foresite Capital continues to demonstrate strong fundraising capabilities, exemplified by the closing of Foresite Capital Fund VI at $1.7 billion in 2022. This substantial capital pool further solidifies their capacity to make impactful investments in the evolving healthcare landscape. The firm's deep expertise in the life sciences, combined with its robust financial resources, positions it as a key partner for entrepreneurs and companies striving to bring transformative healthcare solutions to market.

Investor Profile

Foresite Capital has backed more than 165 startups, with 14 new investments in the last 12 months alone. The firm has led 43 rounds, about 26% of its total and boasts 60 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series C, Series A rounds (top funding stages).
  • Majority of deals are located in United States, United Kingdom, Switzerland.
  • Strong thematic focus on Biotechnology, Health Care, Therapeutics.
  • Led 4 rounds in the past year.
  • Typical check size: $20M – $100M.

Stage Focus

  • Series B (33%)
  • Series C (25%)
  • Series A (13%)
  • Post Ipo Equity (9%)
  • Series D (9%)
  • Series E (3%)
  • Series Unknown (2%)
  • Private Equity (1%)
  • Series F (1%)
  • Seed (1%)

Country Focus

  • United States (88%)
  • United Kingdom (7%)
  • Switzerland (2%)
  • Australia (1%)
  • Canada (1%)
  • Isle of Man (1%)
  • Hong Kong (1%)
  • China (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Therapeutics
  • Medical
  • Life Science
  • Pharmaceutical
  • Biopharma
  • Genetics
  • Health Diagnostics
  • Oncology
circle-line
FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Foresite Capital frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 35
CA
North America, Massachusetts, United States, Boston
Co-Investments: 22
Google Ventures
North America, California, United States, Mountain View
Co-Investments: 23
Casdin Capital
North America, New York, United States, New York
Co-Investments: 21
T. Rowe Price
North America, Maryland, United States, Baltimore
Co-Investments: 22
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 26
Logos Capital
North America, California, United States, San Francisco
Co-Investments: 14
Venrock
North America, California, United States, Palo Alto
Co-Investments: 22
ARCH Venture Partners
North America, Illinois, United States, Chicago
Co-Investments: 19
Fidelity
North America, Massachusetts, United States, Boston
Co-Investments: 26

Which angels does Foresite Capital often collaborate with?

ME
Europe, England, United Kingdom
Shared Deals: 1
RB
North America, Virgin Islands, United States
Shared Deals: 1
AU
Europe, Hallands Lan, Sweden, Kungsbacka
Shared Deals: 1
Mark W. Hahn
North America, North Carolina, United States, Chapel Hill
Shared Deals: 1
RK
North America, California, United States
Shared Deals: 2
MA
North America, California, United States, San Francisco
Shared Deals: 2
VS
North America, Massachusetts, United States, Boston
Shared Deals: 1
AW
North America, California, United States, San Francisco
Shared Deals: 2
David Zaccardelli
North America, United States
Shared Deals: 1
DE
Europe, Zurich, Switzerland, Zürich
Shared Deals: 1

What are some of recent deals done by Foresite Capital?

Inmagene Biopharmaceuticals

San Diego, California, United States

Inmagene is a clinical-stage biotech company developing innovative and differentiated therapies for immunological and inflammatory diseases.

BiopharmaBiotechnologyHealth Care
Post Ipo EquityJul 28, 2025
Amount Raised: $75,000,000
RayThera

San Diego, California, United States

RayThera is dedicated to developing small molecule therapies specifically targeting unmet needs in immunology.

Biotechnology
Series AApr 4, 2025
Amount Raised: $110,000,000
Latigo Biotherapeutics

Thousand Oaks, California, United States

Latigo Biotherapeutics is a clinical-stage biotechnology company that develops novel, non-opioid therapies for chronic pain.

BiotechnologyHealth CareMedicalTherapeutics
Series BMar 17, 2025
Amount Raised: $150,000,000
Eikon Therapeutics

Hayward, California, United States

Eikon Therapeutics is a biopharmaceutical company that develops live-cell resolution microscopy and engineering for drug discovery.

BiotechnologyHealth CareLife ScienceMedical
Series DFeb 26, 2025
Amount Raised: $350,700,000
Abcuro

Newton, Massachusetts, United States

Abcuro develops immunotherapies to treat autoimmunity and cancer.

BiotechnologyHealth CareMedicalTherapeutics
Series CFeb 12, 2025
Amount Raised: $200,000,000
Rapt Therapeutics

South San Francisco, California, United States

Rapt is focused on the discovery and development of novel small-molecule agents to activate the immune system to eradicate cancer.

BiotechnologyHealth CareMedicalPharmaceuticalTherapeutics
Post Ipo EquityDec 23, 2024
Amount Raised: $150,000,000
Ikena Oncology

Boston, Massachusetts, United States

Ikena Oncology develops differentiated therapies to target cancer growth and resistance, focusing on Hippo and RAS signaling pathways.

BiotechnologyHealth CareHealth DiagnosticsOncologyTherapeutics
Post Ipo EquityDec 23, 2024
Amount Raised: $75,000,000
Pleno

San Diego, California, United States

Pleno is a biotechnology company that aims speeding up disease diagnosis and treatment.

BiopharmaBiotechnologyHealth CareHealth Diagnostics
Series BDec 12, 2024
Amount Raised: $25,000,000
Sollis Health

New York, New York, United States

Sollis Health offers concierge medical centers that provide on-demand care for families, including same-day visits and virtual care options.

Health CareHealth DiagnosticsMedicalPersonal Health
Series BDec 5, 2024
Amount Raised: $33,000,000
Avenzo Therapeutics

San Diego, California, United States

Avenzo Therapeutics specializes in the development of oncology therapies for cancer treatment.

BiotechnologyHealth CareMedicalOncologyTherapeutics
Series ANov 18, 2024