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Novo Holdings

Europe, Hovedstaden, Denmark, Hellerup

Description

Novo Holdings, based in Hellerup, Denmark, serves as the holding company for the assets of the Novo Nordisk Foundation, a globally recognized philanthropic enterprise. Its core mission is to manage the Foundation's substantial assets to ensure a stable financial base for its scientific, humanitarian, and social purposes. As a leading global life science investor, Novo Holdings is dedicated to creating long-term value by investing across the entire spectrum of the life science industry, from nascent startups to established global enterprises.

The investment strategy of Novo Holdings is highly diversified, encompassing various stages and types of companies within the life science sector, including pharmaceuticals, biotechnology, medical technology, and industrial biotech. They operate through distinct investment teams, such as Novo Seeds, which focuses on early-stage venture capital primarily in the Nordic region, and Novo Ventures, which targets later-stage venture and growth equity opportunities globally. Additionally, their Principal Investments team undertakes significant, long-term strategic investments, often acquiring controlling or substantial minority stakes in leading life science companies worldwide. This multi-faceted approach allows them to engage with companies at virtually any stage of their development.

Novo Holdings commands significant financial resources, with total assets reported at EUR 111 billion (approximately USD 120 billion) as of the end of 2023. This substantial capital base enables them to deploy considerable sums across their portfolio. Their typical first cheque sizes vary widely depending on the investment strategy. For early-stage companies through Novo Seeds, initial investments can be as low as $1 million. Conversely, their later-stage venture and principal investments can involve initial commitments reaching up to $500 million, reflecting their capacity for large-scale strategic funding. Novo Holdings' commitment extends beyond capital, often providing strategic guidance and leveraging their extensive network to foster the growth and success of their portfolio companies, ultimately contributing to advancements in global health and sustainability.

Investor Profile

Novo Holdings has backed more than 381 startups, with 32 new investments in the last 12 months alone. The firm has led 139 rounds, about 36% of its total and boasts 97 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series A, Series B, Series C rounds (top funding stages).
  • Majority of deals are located in United States, Denmark, United Kingdom.
  • Strong thematic focus on Biotechnology, Health Care, Medical.
  • Led 19 rounds in the past year.
  • Typical check size: $1M – $500M.

Stage Focus

  • Series A (26%)
  • Series B (18%)
  • Series C (16%)
  • Series Unknown (14%)
  • Seed (6%)
  • Post Ipo Equity (5%)
  • Series D (5%)
  • Private Equity (3%)
  • Series E (3%)
  • Series F (1%)

Country Focus

  • United States (47%)
  • Denmark (22%)
  • United Kingdom (8%)
  • Switzerland (5%)
  • Sweden (3%)
  • Germany (3%)
  • France (2%)
  • Canada (2%)
  • Singapore (1%)
  • India (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Medical
  • Pharmaceutical
  • Therapeutics
  • Biopharma
  • Medical Device
  • Life Science
  • Manufacturing
  • Health Diagnostics
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Novo Holdings frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 31
HBM Healthcare Investments
Europe, Zug, Switzerland, Zug
Co-Investments: 18
Surveyor Capital
North America, Illinois, United States, Chicago
Co-Investments: 13
New Enterprise Associates
North America, California, United States, Menlo Park
Co-Investments: 19
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 26
SR One
North America, Massachusetts, United States, Cambridge
Co-Investments: 15
Rock Springs Capital
North America, Maryland, United States, Baltimore
Co-Investments: 14
HealthCap
Europe, Stockholms Lan, Sweden, Stockholm
Co-Investments: 17
Vivo Capital
North America, California, United States, Palo Alto
Co-Investments: 17
Sunstone Life Science Ventures
Europe, Hovedstaden, Denmark, Copenhagen
Co-Investments: 16

Which angels does Novo Holdings often collaborate with?

ME
Europe, England, United Kingdom
Shared Deals: 1
JL
North America, Nevada, United States, Las Vegas
Shared Deals: 1
George Godula
Asia, Shanghai, China, Shanghai
Shared Deals: 1
AU
Europe, Hallands Lan, Sweden, Kungsbacka
Shared Deals: 1
Mark W. Hahn
North America, North Carolina, United States, Chapel Hill
Shared Deals: 1
VS
North America, Massachusetts, United States, Boston
Shared Deals: 1
NP
North America, California, United States, San Francisco
Shared Deals: 1
GC
Europe, Emilia-Romagna, Italy, Parma
Shared Deals: 2
David Zaccardelli
North America, United States
Shared Deals: 1
DE
Europe, Zurich, Switzerland, Zürich
Shared Deals: 1

What are some of recent deals done by Novo Holdings?

Hemab

Copenhagen, Hovedstaden, Denmark

Hemab is a clinical-stage biotech company that develops prophylactic biologic therapies for underserved bleeding and thrombotic.

BiotechnologyLife ScienceMedicalPharmaceutical
Series COct 27, 2025
Amount Raised: $157,000,000
MATR Foods

Copenhagen, Hovedstaden, Denmark

MATR Foods is a food-tech startup that provides fungi-based food ingredients.

Food and BeverageFood ProcessingOrganic Food
Series AOct 21, 2025
Amount Raised: $23,265,255
Expedition Therapeutics

San Francisco, California, United States

Expedition Therapeutics is a biotechnology company that develops novel therapies for inflammatory and respiratory diseases.

BiotechnologyHealth CareLife ScienceTherapeutics
Series AOct 9, 2025
Amount Raised: $165,000,000
Crystalys Therapeutics

San Diego, California, United States

Crystalys Therapeutics is a clinical-stage biopharmaceutical company transforming the treatment of gout.

BiopharmaHealth CareMedicalTherapeutics
Series ASep 30, 2025
Amount Raised: $205,000,000
The Protein Brewery

Breda, Noord-Brabant, The Netherlands

The Protein Brewery specializes in developing and making animal-free-based protein in a sustainable way.

BiotechnologyFood ProcessingLife Science
Series BSep 22, 2025
Amount Raised: $35,202,095
Reunion Neuroscience

Toronto, Ontario, Canada

Reunion Neuroscience is a clinical-stage pharmaceutical company developing therapeutic solutions for underserved mental health conditions.

BiotechnologyMental HealthNeurosciencePharmaceutical
Series ASep 16, 2025
Amount Raised: $133,000,000
AMSilk

Planegg, Bayern, Germany

AMSilk produces and distributes high-quality silk biopolymers.

BiotechnologyCosmetics
Series UnknownSep 9, 2025
Amount Raised: $35,122,349
Phasecraft

London, England, United Kingdom

Phasecraft develops quantum algorithms and related intellectual property for scientific and industrial applications.

ComputerInformation TechnologyQuantum ComputingSoftware
Series BSep 2, 2025
Amount Raised: $34,000,000
BBOT

Palo Alto, California, United States

BBOT is a clinical-stage biopharmaceutical company advancing a pipeline of novel therapeutics targeting RAS and PI3Kα malignancies.

BiopharmaTherapeutics
Post Ipo EquityAug 11, 2025
Amount Raised: $261,000,000
Mission Bio

San Francisco, California, United States

Mission Bio develops only single-cell multi-omics platform integrating genotype and phenotype for cancer research and biomarker development.

BioinformaticsBiotechnologyGeneticsHealth CareOncology
Series UnknownAug 5, 2025