ENISA logo

ENISA

Europe, Madrid, Spain, Madrid

Description

ENISA (Empresa Nacional de Innovación, S.A.) is a prominent public company based in Madrid, Spain, operating under the Ministry of Industry, Trade and Tourism. Its core mission is to actively foster the growth of viable and innovative technology projects within the Spanish entrepreneurial landscape. Unlike traditional venture capital firms, ENISA primarily provides funding through participatory loans, a unique financial instrument that blends characteristics of debt and equity. This approach allows for a flexible repayment structure, where part of the interest rate is often linked to the company's financial performance, thereby aligning the repayment burden with the company's success and typically not requiring additional guarantees beyond the project's viability.

ENISA targets a broad spectrum of Spanish small and medium-sized enterprises (SMEs) and startups, particularly those demonstrating high growth potential and a strong innovative component. They offer distinct financing lines tailored to different stages of business development. The "Jóvenes Emprendedores" and "Emprendedores" lines typically support early-stage companies and new ventures, while the "Crecimiento" line is designed for more established businesses seeking significant expansion capital. A key characteristic of ENISA's funding model is its non-dilutive nature; the company does not take an equity stake in the businesses it supports, allowing founders to retain full ownership and control.

The organization plays a crucial role in stimulating the Spanish economy and its innovation ecosystem. Its financial support has significantly contributed to the creation and consolidation of numerous startups across various sectors. For instance, in 2022, ENISA approved a substantial 765 loans, injecting a total of €140.2 million (approximately $151.4 million USD) into the Spanish entrepreneurial fabric. This commitment continued into 2023, with 751 loans approved, totaling €128.5 million (approximately $138.8 million USD) in disbursed funds. These figures underscore ENISA's consistent and substantial impact on fostering innovation and job creation throughout Spain.

Investor Profile

ENISA has backed more than 194 startups, with 19 new investments in the last 12 months alone. The firm has led 78 rounds, about 40% of its total and boasts 5 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Debt Financing, Seed, Pre Seed rounds (top funding stages).
  • Majority of deals are located in Spain, United States, France.
  • Strong thematic focus on Software, Information Technology, Artificial Intelligence (AI).
  • Led 12 rounds in the past year.
  • Typical check size: $27K – $1.6M.

Stage Focus

  • Debt Financing (35%)
  • Seed (32%)
  • Pre Seed (12%)
  • Grant (8%)
  • Series Unknown (6%)
  • Series A (3%)
  • Convertible Note (1%)
  • Angel (1%)
  • Non Equity Assistance (1%)
  • Equity Crowdfunding (1%)

Country Focus

  • Spain (94%)
  • United States (2%)
  • France (1%)
  • Portugal (1%)
  • Germany (1%)
  • Morocco (1%)
  • The Netherlands (1%)
  • Colombia (1%)

Industry Focus

  • Software
  • Information Technology
  • Artificial Intelligence (Ai)
  • Health Care
  • E-commerce
  • Saas
  • Internet
  • Food And Beverage
  • Fintech
  • Apps
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does ENISA frequently co-invest with?

Capital Cell
Europe, Catalonia, Spain, Barcelona
Co-Investments: 3
Antai Ventures
Europe, Catalonia, Spain, Barcelona
Co-Investments: 4
4Founders Capital
Europe, Catalonia, Spain, Barcelona
Co-Investments: 3
TE
Europe, Canarias, Spain, Las Palmas De Gran Canaria
Co-Investments: 7
ICF Capital
Europe, Catalonia, Spain, Barcelona
Co-Investments: 6
AN
Europe, Canarias, Spain, Las Palmas De Gran Canaria
Co-Investments: 5
Wayra
Europe, Madrid, Spain, Madrid
Co-Investments: 5
VI
Europe, Comunidad Valenciana, Spain, Valencia
Co-Investments: 5
Draper B1
Europe, Comunidad Valenciana, Spain, Valencia
Co-Investments: 8
Co-Investments: 6

Which angels does ENISA often collaborate with?

JU
Europe, Madrid, Spain, Madrid
Shared Deals: 1
SB
Europe, Madrid, Spain, Madrid
Shared Deals: 1
AA
Europe, Catalonia, Spain, Barcelona
Shared Deals: 3
TB
North America, California, United States, Los Angeles
Shared Deals: 1
AM
Europe, Andalucia, Spain, Marbella
Shared Deals: 2
LB
Europe, Oost-Vlaanderen, Belgium, Gent
Shared Deals: 1
RM
North America, Florida, United States, Tampa
Shared Deals: 1
Fernando Jaime Fernández
North America, Nuevo Leon, Mexico, Monterrey
Shared Deals: 1
BL
North America, New York, United States, New York
Shared Deals: 1
FN
Europe, Madrid, Spain, Madrid
Shared Deals: 1

What are some of recent deals done by ENISA?

Opportunity Health

Sangüesa, Navarra, Spain

Opportunity Health is an innovative Navarrese company

Health Care
SeedJan 28, 2026
Amount Raised: $397,793
Pragmatech AI Solutions

Oviedo, Florida, United States

Pragmatech AI Solutions specializes on artificial intelligence solutions for infectious diseases, microbiology, and pharmacology.

Debt FinancingDec 30, 2025
Amount Raised: $211,924
Go—PopUp

Barcelona, Catalonia, Spain

Go—PopUp is a booking service for renting shops, malls, and promotion venues for pop-up stores marketing promotions.

Brand MarketingMarketplaceProduct ManagementRetailShopping
Debt FinancingDec 10, 2025
Wiemspro

Málaga, Andalucia, Spain

Wiemspro offers a complete wireless electrostimulation system.

FitnessWearablesWellness
Debt FinancingDec 1, 2025
Amount Raised: $278,642
Uxia

Barcelona, Catalonia, Spain

Uxia offers an AI-powered platform for rapid UX/UI user testing using synthetic users that imitate real-world behaviours.

Artificial Intelligence (AI)SoftwareUX Design
Debt FinancingNov 27, 2025
Hair Up Laser

Barcelona, Catalonia, Spain

Hair Up Laser is a plattform specializing in medical products for the treatment of alopecia.

Health CareMedical
GrantNov 24, 2025
HOLO

Barcelona, Catalonia, Spain

HOLO Health is a startup revolutionizing personalized health by blending advanced laboratory testing.

Enterprise SoftwareHealth CareHospitalWellness
Pre SeedNov 13, 2025
Amount Raised: $1,163,030

Callnak specializes in designing and producing 3D-printed shoes that integrate cutting-edge technology, eco-friendliness, and customization.

3D TechnologyBusiness IntelligenceWeb Design
SeedNov 11, 2025
Amount Raised: $231,750
Kabilio

Barcelona, Catalonia, Spain

Kabilio uses AI to automate accounting and tax processes.

AccountingArtificial Intelligence (AI)Financial Services
Debt FinancingNov 5, 2025
Amount Raised: $229,822
Fly

Madrid, Madrid, Spain

Fly help transform surfers into advanced professionals with surfboards and accessories 100% focused on accelerating their learning.

ManufacturingSportsSurfing
Debt FinancingOct 22, 2025
Amount Raised: $213,572

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