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LYFE Capital

Asia, Central Region, Singapore, Singapore

Description

LYFE Capital is a prominent Transpacific healthcare investment firm with a substantial asset under management (AUM) of approximately US$2 billion across multiple funds. Headquartered in Singapore, with additional offices in Shanghai, Hong Kong, and San Francisco, the firm strategically positions itself to capitalize on innovative and high-growth opportunities within the global healthcare sector. Their investment philosophy centers on identifying companies with strong potential for market disruption and significant patient impact, primarily focusing on the dynamic markets of the United States and China.

The firm's investment strategy is broad yet specialized, encompassing various segments of the healthcare value chain. LYFE Capital primarily targets growth equity, late-stage venture, and private equity opportunities, indicating a preference for more mature companies that have demonstrated product-market fit and are poised for significant scaling. Their portfolio spans critical areas such as biopharmaceuticals, medical devices, diagnostics, and healthcare services. This diversified approach allows them to mitigate risk while maximizing exposure to different growth drivers within the healthcare ecosystem, leveraging their deep industry expertise and extensive network.

Given their substantial AUM and focus on growth and late-stage investments, LYFE Capital typically deploys significant capital into its portfolio companies. While specific figures can vary based on the opportunity and stage, the firm's initial cheque sizes generally range from US$15 million to US$75 million. They often act as lead or co-lead investors in substantial funding rounds, as evidenced by their participation in multi-hundred-million-dollar rounds for companies like Everest Medicines and Ascentage Pharma. This strategic capital deployment is complemented by active involvement, offering portfolio companies operational guidance and access to their transpacific network to facilitate expansion and market penetration.

Investor Profile

LYFE Capital has backed more than 25 startups, with 3 new investments in the last 12 months alone. The firm has led 5 rounds, about 20% of its total and boasts 9 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series A, Series C rounds (top funding stages).
  • Majority of deals are located in United States, China, France.
  • Strong thematic focus on Biotechnology, Health Care, Therapeutics.
  • Led 1 rounds in the past year.
  • Typical check size: $15M – $75M.

Stage Focus

  • Series B (40%)
  • Series A (16%)
  • Series C (12%)
  • Series E (8%)
  • Series D (8%)
  • Post Ipo Equity (4%)
  • Series Unknown (4%)
  • Seed (4%)
  • Series F (4%)

Country Focus

  • United States (60%)
  • China (24%)
  • France (8%)
  • Israel (4%)
  • United Kingdom (4%)

Industry Focus

  • Biotechnology
  • Health Care
  • Therapeutics
  • Pharmaceutical
  • Medical
  • Genetics
  • Medical Device
  • Manufacturing
  • Biopharma
  • Health Diagnostics
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does LYFE Capital frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 7
Alexandria Venture Investments
North America, California, United States, Pasadena
Co-Investments: 4
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 5
Agilent Technologies
North America, California, United States, Santa Clara
Co-Investments: 2
Argonautic Ventures
North America, Washington, United States, Seattle
Co-Investments: 2
iSelect Fund
North America, Missouri, United States, St Louis
Co-Investments: 2
Codexis
North America, California, United States, Redwood City
Co-Investments: 2
HongShan
Asia, Beijing, China, Beijing
Co-Investments: 4
Legend Star
Asia, Beijing, China, Beijing
Co-Investments: 3
Lilly Asia Ventures
Asia, Shanghai, China, Shanghai
Co-Investments: 4

Which angels does LYFE Capital often collaborate with?

Zohar Zisapel
Asia, Tel Aviv, Israel, Tel Aviv
Shared Deals: 1

What are some of recent deals done by LYFE Capital?

Neurona Therapeutics

San Francisco, California, United States

Neurona Therapeutics develops cell therapies for neurological disorders, focusing on treatments like NRTX-1001 for epilepsy.

BiotechnologyHealth CareTherapeutics
Series FApr 3, 2025
Amount Raised: $102,000,000
Verdiva Bio

London, England, United Kingdom

Verdiva Bio creates cutting-edge treatments that improve results for patients with obesity and cardiometabolic diseases.

BiotechnologyHealth CareMedical
Series AJan 9, 2025
Amount Raised: $411,000,000
CytoTronics

Boston, Massachusetts, United States

CytoTronics is designing and developing cell culture plates with embedded high-density electronic systems.

Test and Measurement
SeedSep 5, 2024
Amount Raised: $13,500,000
Precision BioSciences

Durham, North Carolina, United States

Precision BioSciences is a biotechnology company dedicated to improving life.

BiotechnologyGeneticsHealth CareMedical
Post Ipo EquityMar 1, 2024
Amount Raised: $40,000,000
ProfoundBio

Seattle, Washington, United States

ProfoundBio is a developer of targeted therapeutics intended for patients with cancer.

BiotechnologyOncologyTherapeutics
Series BFeb 13, 2024
Amount Raised: $112,000,000
Neurona Therapeutics

San Francisco, California, United States

Neurona Therapeutics develops cell therapies for neurological disorders, focusing on treatments like NRTX-1001 for epilepsy.

BiotechnologyHealth CareTherapeutics
Series EFeb 8, 2024
Amount Raised: $120,000,000
Kyverna Therapeutics

Berkeley, California, United States

Kyverna Therapeutics is pioneering a new class of therapies and cures for serious autoimmune diseases.

BiotechnologyLife ScienceTherapeutics
Series BAug 3, 2023
Amount Raised: $60,000,000
Noah Medical

San Carlos, California, United States

Noah Medical develops medical robotics using its next-generation robotic platform for patient diagnosis and treatment.

Health CareHealth DiagnosticsMedical Device
Series BApr 19, 2023
Amount Raised: $150,000,000
iECURE

Philadelphia, Pennsylvania, United States

iECURE is a mutation-agnostic in vivo gene editing company striving to cure devastating diseases with high unmet needs.

BiotechnologyGenetics
Series ANov 30, 2022
Amount Raised: $65,000,000
Baiying Bio

Beijing, Beijing, China

Baiying Bio is a research and development outsourcing service provider.

BiotechnologyOutsourcingService Industry
Series BAug 31, 2022
Amount Raised: $72,564,728