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Mayfield Fund

North America, California, United States, Menlo Park

Description

Mayfield Fund is a distinguished early-stage venture capital firm, founded in 1969, making it one of the longest-standing VC firms in Silicon Valley. With a rich history spanning over five decades, Mayfield has consistently focused on partnering with entrepreneurs from the earliest stages, often at the seed or Series A rounds. The firm's investment thesis centers on 'People-First Investing,' emphasizing the importance of visionary founders and strong teams. Mayfield's portfolio reflects a strategic focus on transformative technologies across several key sectors, including enterprise software, deep technology, and increasingly, companies addressing human and planetary health challenges.

Over its extensive history, Mayfield has raised numerous funds, demonstrating sustained commitment to early-stage innovation. For instance, in 2022, the firm announced Mayfield XVII, a $525 million fund, alongside Mayfield Select II, a $150 million fund, bringing their total capital raised to over $7 billion across all funds. This substantial capital base allows Mayfield to provide significant support to its portfolio companies, not just through initial funding but also through follow-on rounds as they scale. The firm prides itself on its hands-on approach, leveraging its deep network and operational expertise to help founders navigate critical growth phases.

Mayfield's investment strategy is characterized by its commitment to backing disruptive ideas that have the potential to create new markets or redefine existing ones. Their portfolio includes notable successes across various technology cycles, from foundational enterprise software to cutting-edge AI and biotech solutions. The firm typically leads or co-leads early-stage rounds, providing capital and strategic guidance to help companies achieve product-market fit and accelerate their growth trajectories. Their long-term perspective and focus on foundational technologies underscore their role as a significant player in the early-stage venture ecosystem.

Investor Profile

Mayfield Fund has backed more than 698 startups, with 25 new investments in the last 12 months alone. The firm has led 215 rounds, about 31% of its total and boasts 195 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series A, Series C rounds (top funding stages).
  • Majority of deals are located in United States, India, China.
  • Strong thematic focus on Software, Enterprise Software, Internet.
  • Led 15 rounds in the past year.
  • Typical check size: $1M – $15M.

Stage Focus

  • Series B (24%)
  • Series A (24%)
  • Series C (16%)
  • Series Unknown (13%)
  • Seed (9%)
  • Series D (6%)
  • Series E (3%)
  • Series F (1%)
  • Undisclosed (1%)
  • Pre Seed (1%)

Country Focus

  • United States (85%)
  • India (10%)
  • China (2%)
  • United Kingdom (2%)

Industry Focus

  • Software
  • Enterprise Software
  • Internet
  • Information Technology
  • Saas
  • E-commerce
  • Artificial Intelligence (Ai)
  • Manufacturing
  • Mobile
  • Health Care
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Mayfield Fund frequently co-invest with?

Sequoia Capital
North America, California, United States, Menlo Park
Co-Investments: 18
Kleiner Perkins
North America, California, United States, Menlo Park
Co-Investments: 24
New Enterprise Associates
North America, California, United States, Menlo Park
Co-Investments: 19
GSR Ventures
North America, California, United States, Menlo Park
Co-Investments: 17
Norwest Venture Partners
North America, California, United States, Palo Alto
Co-Investments: 19
Foundation Capital
North America, California, United States, Palo Alto
Co-Investments: 17
Trinity Ventures
North America, California, United States, Menlo Park
Co-Investments: 28
U.S. Venture Partners
North America, California, United States, Menlo Park
Co-Investments: 25
Accel
North America, California, United States, Palo Alto
Co-Investments: 28
Redpoint
North America, California, United States, Menlo Park
Co-Investments: 17

Which angels does Mayfield Fund often collaborate with?

TW
North America, California, United States, San Francisco
Shared Deals: 5
RM
North America, California, United States, San Francisco
Shared Deals: 8
PC
North America, California, United States, Los Angeles
Shared Deals: 4
KH
North America, California, United States, San Francisco
Shared Deals: 2
EW
North America, California, United States, San Francisco
Shared Deals: 2
NR
North America, California, United States, San Francisco
Shared Deals: 4
CP
North America, California, United States
Shared Deals: 2
BH
North America, California, United States, Palo Alto
Shared Deals: 2
MM
North America, California, United States, Santa Clara
Shared Deals: 2
SP
North America, California, United States, San Francisco
Shared Deals: 3

What are some of recent deals done by Mayfield Fund?

Obot AI

Cupertino, California, United States

Obot AI is developing an open-source Enterprise MCP Gateway to facilitate the rapid adoption of AI

Software
SeedSep 23, 2025
Amount Raised: $35,000,000
Numeral

San Francisco, California, United States

Numeral provides a platform that automates the sales tax process for e-commerce and SaaS businesses.

ComplianceFinancial ServicesFinTechInformation TechnologySoftware
Series BSep 18, 2025
Amount Raised: $35,000,000
Upscale AI

Santa Clara, California, United States

Upscale AI redefines networking with purpose-built solutions for high-performance compute.

Artificial Intelligence (AI)Network Security
SeedSep 17, 2025
Amount Raised: $100,000,000
Highbeam

New York, New York, United States

Banking that helps brand owners make smarter decisions

Business DevelopmentFinTechInformation ServicesOnline Portals
Series ASep 9, 2025
Amount Raised: $30,000,000
Prorata.AI

Pasadena, California, United States

ProRata specializes in building AI-powered search and advertising solutions that prioritize content attribution for the original creators.

AdvertisingArtificial Intelligence (AI)ContentGenerative AISoftware
Series BSep 5, 2025
Amount Raised: $40,000,000
OpenLight

Goleta, California, United States

OpenLight is a manufacturing company that specializes in custom Photonic Application-Specific Integrated Circuit (PASIC) chip design.

Information TechnologyInternet of ThingsManufacturingQuantum Computing
Series AAug 26, 2025
Amount Raised: $34,000,000
Mission Bio

San Francisco, California, United States

Mission Bio develops only single-cell multi-omics platform integrating genotype and phenotype for cancer research and biomarker development.

BioinformaticsBiotechnologyGeneticsHealth CareOncology
Series UnknownAug 5, 2025
Scrunch AI

Los Angeles, California, United States

Scrunch AI, a platform designed to help businesses optimize their presence in AI-driven search.

Information TechnologyInternet
Series AJul 22, 2025
Amount Raised: $15,000,000
Zucca

Seattle, Washington, United States

Zucca provides quickest and smartest method for bringing new food and drink products to market.

Information TechnologyInternet
SeedJul 16, 2025
Amount Raised: $5,000,000
Sema4.ai

Atlanta, Georgia, United States

Sema4.ai is an AI platform that empowers organizations to build, deploy, and manage agents designed to transform knowledge work.

Artificial Intelligence (AI)Generative AISoftwareWeb Development
Series AJun 4, 2025
Amount Raised: $25,000,000