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Prolog Ventures

North America, Missouri, United States, St Louis

Description

Prolog Ventures is a venture capital firm based in St. Louis, United States, dedicated to investing in companies that promote healthy lives in a healthy world. Established in 2000, the firm has built a robust portfolio focused on the natural products, health and wellness, food, and sustainability sectors. Their investment philosophy centers on supporting innovative businesses that address critical consumer needs and contribute positively to environmental and personal well-being.

The firm typically targets early-stage companies, ranging from Seed to Series A rounds, where they can provide not just capital but also strategic guidance and operational support. Prolog Ventures seeks out companies with strong management teams, disruptive technologies or business models, and significant market potential within their niche. Their long-standing presence in the venture ecosystem, having been founded over two decades ago, speaks to their deep experience and commitment to their specialized investment areas.

Prolog Ventures manages over $100 million in capital, which they deploy to foster growth in their portfolio companies. They have made over 40 investments across various stages, demonstrating a consistent track record of identifying and backing promising ventures. The firm's hands-on approach involves working closely with founders to navigate challenges, scale operations, and achieve market leadership, leveraging their extensive network and industry expertise.

Investor Profile

Prolog Ventures has backed more than 72 startups, with 0 new investments in the last 12 months alone. The firm has led 14 rounds, about 19% of its total and boasts 15 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series Unknown, Series A rounds (top funding stages).
  • Majority of deals are located in United States, Canada.
  • Strong thematic focus on Biotechnology, Health Care, Medical Device.
  • Typical check size: $500K – $5M.

Stage Focus

  • Series B (26%)
  • Series Unknown (24%)
  • Series A (22%)
  • Series C (11%)
  • Series D (7%)
  • Series E (3%)
  • Debt Financing (3%)
  • Series F (1%)
  • Series G (1%)
  • Seed (1%)

Country Focus

  • United States (99%)
  • Canada (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Medical Device
  • Medical
  • Manufacturing
  • Food And Beverage
  • Agriculture
  • Life Science
  • Therapeutics
  • Service Industry
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Prolog Ventures frequently co-invest with?

Prelude Ventures
North America, California, United States, San Francisco
Co-Investments: 7
St. Louis Arch Angels
North America, Missouri, United States, St Louis
Co-Investments: 5
MT
North America, Missouri, United States, Jefferson City
Co-Investments: 4
Sante Ventures
North America, Texas, United States, Austin
Co-Investments: 4
Cultivation Capital
North America, Missouri, United States, St Louis
Co-Investments: 5
Unilever Ventures
Europe, England, United Kingdom, London
Co-Investments: 4
Burrill & Company
North America, California, United States, San Francisco
Co-Investments: 9
Advantage Capital
North America, Louisiana, United States, New Orleans
Co-Investments: 7
Heron Capital
North America, Indiana, United States, Carmel
Co-Investments: 5
GS
North America, California, United States, Mill Valley
Co-Investments: 7

Which angels does Prolog Ventures often collaborate with?

MR
North America, Missouri, United States, St Louis
Shared Deals: 1
SS
North America, California, United States, Los Angeles
Shared Deals: 1
RB
North America, Illinois, United States, Chicago
Shared Deals: 1

What are some of recent deals done by Prolog Ventures?

Benson Hill

St Louis, Missouri, United States

Benson Hill is a provider of crop design platform to develop healthier and more sustainable food and ingredients.

AgricultureAgTechArtificial Intelligence (AI)BiotechnologyMachine Learning
Series DOct 29, 2020
Amount Raised: $150,000,000
CleanSlate UV

Toronto, Ontario, Canada

CleanSlate UV disinfects phones, tablets & other mobile devices in 30 seconds, preventing the spread of bacteria & keeping devices clean.

BiotechnologyElectronicsMedical DevicemHealth
Series AApr 15, 2020
Amount Raised: $7,000,000
Covercress

St Louis, Missouri, United States

Covercress is a biotechnology company that manufactures an oilseed crop for food, bioenergy, and cattle feed.

Animal FeedBiotechnologyFuelIndustrialNutritionOil and GasRenewable Energy
Series UnknownApr 13, 2020
Amount Raised: $5,000,000
Kinnos

Brooklyn, New York, United States

Kinnos is a biotechnology company that makes it easy to use disinfectants correctly.

BiotechnologyCleanTechHealth Care
Series AMar 5, 2020
Amount Raised: $6,000,000
BioClarity

San Diego, California, United States

BioClarity is a three-step acne fighting treatment designed to give you a new kind of confidence—natural confidence.

Consumer Goods
Series UnknownMay 14, 2019
Amount Raised: $13,000,000
SchoolCare

New York, New York, United States

SchoolCare delivers free health technology for K-12 public schools to help school nurses deliver care and keep students safe.

EducationHealth CareInternet
Series CFeb 15, 2019
Amount Raised: $24,340,000
Covercress

St Louis, Missouri, United States

Covercress is a biotechnology company that manufactures an oilseed crop for food, bioenergy, and cattle feed.

Animal FeedBiotechnologyFuelIndustrialNutritionOil and GasRenewable Energy
Series UnknownNov 13, 2018
Amount Raised: $2,000,000
Toma Biosciences

Foster City, California, United States

Toma Biosciences is a biotechnology company that develops and provides DNA-based cancer testing technology.

Series CJul 21, 2018
Amount Raised: $3,600,000
Spindrift

Newton, Massachusetts, United States

Spindrift is a food and beverage company that produces a line of unsweetened sparkling beverages made with real squeezed fruit.

Food and BeverageFruit
Series BMar 15, 2018
Amount Raised: $20,000,000
SchoolCare

New York, New York, United States

SchoolCare delivers free health technology for K-12 public schools to help school nurses deliver care and keep students safe.

EducationHealth CareInternet
Series BJan 17, 2018
Amount Raised: $16,000,000