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Sofinnova Investments

North America, California, United States, Menlo Park

Description

Sofinnova Investments, headquartered in Menlo Park, California, is a prominent venture capital firm with a specialized focus on the life sciences sector. The firm primarily invests in biopharmaceuticals, medical devices, and diagnostics, demonstrating a deep commitment to advancing healthcare innovation. Sofinnova's investment strategy spans various stages, from seed and early-stage startups, including Series A rounds and first venture rounds, to more mature mid-stage companies and corporate spinouts. This broad approach allows them to support companies throughout their growth trajectory, from foundational research to clinical development and commercialization.

With a history rooted in European venture capital, Sofinnova Investments has evolved into a significant player in the US market, leveraging its extensive network and scientific expertise. The firm is known for its hands-on approach, often taking active roles on the boards of its portfolio companies and providing strategic guidance beyond just capital. Their team comprises seasoned professionals with backgrounds in science, medicine, and finance, enabling them to conduct thorough due diligence and provide valuable operational support to innovative life science ventures.

Sofinnova Investments typically deploys substantial capital into its portfolio companies. While specific figures can vary based on the stage and needs of the company, their initial investments often fall within a range suitable for significant early-stage development and subsequent growth. For instance, their typical first check sizes can range from approximately $5 million for seed or early-stage rounds to upwards of $30 million for more mature Series B or C rounds, reflecting their capacity to lead or co-lead substantial financing rounds. This financial commitment is often complemented by follow-on investments as companies achieve key milestones, underscoring their long-term partnership approach.

The firm's portfolio showcases a diverse array of companies working on groundbreaking therapies and technologies, from oncology and rare diseases to neurological disorders and cardiovascular health. Sofinnova's consistent investment in high-potential life science companies underscores its dedication to fostering innovation that addresses unmet medical needs and improves patient outcomes. Their strategic capital deployment and industry expertise position them as a key partner for entrepreneurs in the dynamic and capital-intensive life sciences industry.

Investor Profile

Sofinnova Investments has backed more than 279 startups, with 5 new investments in the last 12 months alone. The firm has led 66 rounds, about 24% of its total and boasts 118 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series Unknown, Series B, Series A rounds (top funding stages).
  • Majority of deals are located in United States, France, The Netherlands.
  • Strong thematic focus on Biotechnology, Health Care, Pharmaceutical.
  • Typical check size: $5M – $30M.

Stage Focus

  • Series Unknown (24%)
  • Series B (23%)
  • Series A (20%)
  • Series C (15%)
  • Series D (9%)
  • Post Ipo Equity (4%)
  • Series E (3%)
  • Seed (1%)
  • Private Equity (1%)
  • Series F (1%)

Country Focus

  • United States (81%)
  • France (8%)
  • The Netherlands (2%)
  • Switzerland (2%)
  • United Kingdom (2%)
  • Ireland (1%)
  • Germany (1%)
  • Saint-Martin (France) (1%)
  • China (1%)
  • Belgium (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Pharmaceutical
  • Therapeutics
  • Medical
  • Biopharma
  • Software
  • Life Science
  • Oncology
  • Medical Device
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Sofinnova Investments frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 23
venBio Partners
North America, California, United States, San Francisco
Co-Investments: 12
CA
North America, Massachusetts, United States, Boston
Co-Investments: 13
Canaan Partners
North America, California, United States, Menlo Park
Co-Investments: 15
New Enterprise Associates
North America, California, United States, Menlo Park
Co-Investments: 18
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 18
Alta Partners
North America, Mississippi, United States, Jackson
Co-Investments: 14
Rock Springs Capital
North America, Maryland, United States, Baltimore
Co-Investments: 17
Sofinnova Partners
Europe, Ile-de-France, France, Paris
Co-Investments: 17
Vivo Capital
North America, California, United States, Palo Alto
Co-Investments: 19

Which angels does Sofinnova Investments often collaborate with?

SH
North America, North Carolina, United States, Raleigh
Shared Deals: 1
SK
North America, California, United States, Los Angeles
Shared Deals: 1
GD
North America, Massachusetts, United States, Lexington
Shared Deals: 1
MR
North America, California, United States, Hermosa Beach
Shared Deals: 1
JF
North America, California, United States
Shared Deals: 1
RK
North America, California, United States, Los Angeles
Shared Deals: 1

What are some of recent deals done by Sofinnova Investments?

ARTBIO

Cambridge, Massachusetts, United States

ARTBIO is a clinical-stage radiopharmaceutical biotechnology business that is working to create a new class of alpha radioligand medicines.

BiotechnologyHealth CareHospitalMedicalMedical DevicePharmaceutical
Series BJul 29, 2025
Amount Raised: $132,000,000
Edgewise Therapeutics

Boulder, Colorado, United States

Edgewise Therapeutics is a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization.

BiopharmaBiotechnologyHealth Care
Post Ipo EquityApr 2, 2025
Amount Raised: $200,000,000
Atsena Therapeutics

Durham, North Carolina, United States

Atsena Therapeutics is a clinical-stage gene therapy company that develops novel treatments for inherited forms of blindness.

BiotechnologyHealth CareTherapeutics
Series CApr 2, 2025
Amount Raised: $150,000,000
Avenzo Therapeutics

San Diego, California, United States

Avenzo Therapeutics specializes in the development of oncology therapies for cancer treatment.

BiotechnologyHealth CareMedicalOncologyTherapeutics
Series ANov 18, 2024
Axonis Therapeutics

Boston, Massachusetts, United States

Axonis Therapeutics is a neuro-focused biotechnology company that focuses on the development of novel neuromedicines.

BiotechnologyLife ScienceMedical
Series AOct 30, 2024
Amount Raised: $115,000,000
Seaport Therapeutics

Boston, Massachusetts, United States

Seaport Therapeutics operates as a clinical stage biopharmaceutical company.

BiotechnologyPharmaceuticalTherapeutics
Series BOct 21, 2024
Amount Raised: $225,000,000
Marea Therapeutics

San Francisco, California, United States

Marea is a biotechnology firm that uses the advancements in human genetics next-generation medications for cardiometabolic illnesses.

BiotechnologyGeneticsLife Science
Series BJun 18, 2024
Amount Raised: $190,000,000
Seaport Therapeutics

Boston, Massachusetts, United States

Seaport Therapeutics operates as a clinical stage biopharmaceutical company.

BiotechnologyPharmaceutical
Series AApr 9, 2024
Amount Raised: $100,000,000
Aeovian Pharmaceuticals

San Francisco, California, United States

Aeovian Pharmaceuticals aims to discover, develop, and commercialize therapeutics for the treatment of rare and age-related diseases.

BiopharmaBiotechnologyHealth CarePharmaceutical
Series AMar 28, 2024
Amount Raised: $50,000,000
Avenzo Therapeutics

San Diego, California, United States

Avenzo Therapeutics specializes in the development of oncology therapies for cancer treatment.

BiotechnologyHealth CareMedicalOncologyTherapeutics
Series AMar 26, 2024
Amount Raised: $150,000,000