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Hercules Capital

North America, California, United States, San Mateo

Description

Hercules Capital stands as a prominent specialty finance company and the leading publicly traded business development company (BDC) focused on providing venture debt financing to innovative, high-growth companies. Headquartered in San Mateo, California, the firm primarily targets companies across the technology, life sciences, and sustainable and renewable technology sectors. Unlike traditional venture capital firms that primarily offer equity, Hercules Capital provides a crucial alternative financing solution, enabling companies to secure capital without significant equity dilution, which is particularly attractive for founders looking to retain ownership.

The firm's investment strategy centers on offering flexible debt facilities tailored to the specific needs of its portfolio companies, spanning various stages from venture-backed startups to more mature, pre-IPO companies. Hercules Capital typically provides initial commitments ranging from approximately $5 million to $50 million, though their capacity can extend significantly higher for larger, later-stage enterprises. Their financing solutions often include warrants or equity participation, aligning their interests with the long-term success of their portfolio companies while primarily generating returns through interest income.

Since its inception, Hercules Capital has demonstrated significant scale and impact within the venture ecosystem. The firm has committed over $18 billion in capital to more than 600 companies, showcasing its extensive reach and experience in supporting a diverse range of innovative businesses. As of late 2023, Hercules Capital managed total assets of approximately $4.0 billion, underscoring its robust financial position and continued ability to deploy substantial capital. This makes them a critical partner for companies seeking non-dilutive growth capital, complementing traditional equity funding rounds.

Investor Profile

Hercules Capital has backed more than 263 startups, with 14 new investments in the last 12 months alone. The firm has led 131 rounds, about 50% of its total and boasts 152 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Debt Financing, Post Ipo Debt, Series Unknown rounds (top funding stages).
  • Majority of deals are located in United States, United Kingdom, Canada.
  • Strong thematic focus on Biotechnology, Health Care, Pharmaceutical.
  • Led 10 rounds in the past year.
  • Typical check size: $5M – $50M.

Stage Focus

  • Debt Financing (38%)
  • Post Ipo Debt (36%)
  • Series Unknown (11%)
  • Series E (3%)
  • Series C (3%)
  • Series D (3%)
  • Post Ipo Equity (2%)
  • Series B (1%)
  • Series F (1%)
  • Private Equity (1%)

Country Focus

  • United States (86%)
  • United Kingdom (4%)
  • Canada (3%)
  • Switzerland (1%)
  • Israel (1%)
  • Germany (1%)
  • The Netherlands (1%)
  • Australia (1%)
  • Spain (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Pharmaceutical
  • Medical
  • Software
  • Therapeutics
  • Manufacturing
  • Medical Device
  • Biopharma
  • Enterprise Software
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Hercules Capital frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 3
Kleiner Perkins
North America, California, United States, Menlo Park
Co-Investments: 3
InterWest Partners
North America, California, United States, Menlo Park
Co-Investments: 5
New Enterprise Associates
North America, California, United States, Menlo Park
Co-Investments: 3
Scale Venture Partners
North America, California, United States, Foster City
Co-Investments: 3
Silicon Valley Bank
North America, California, United States, Santa Clara
Co-Investments: 12
Frazier Healthcare Partners
North America, Washington, United States, Seattle
Co-Investments: 3
Armentum Partners
North America, California, United States, San Francisco
Co-Investments: 4
JP Morgan
North America, New York, United States, New York
Co-Investments: 3
Venrock
North America, California, United States, Palo Alto
Co-Investments: 3

Which angels does Hercules Capital often collaborate with?

AH
Europe, Bayern, Germany, Munich
Shared Deals: 1
RD
North America, Indiana, United States, Indianapolis
Shared Deals: 1
PT
North America, California, United States, San Francisco
Shared Deals: 1
MD
North America, California, United States, San Francisco
Shared Deals: 1
AD
North America, California, United States, San Francisco
Shared Deals: 1
SS
North America, Washington, United States, Redmond
Shared Deals: 1

What are some of recent deals done by Hercules Capital?

Dyne Therapeutics

Cambridge, Massachusetts, United States

Dyne Therapeutics is a developer of targeted therapies intended for serious muscle diseases.

BiotechnologyHealth CareMedicalPharmaceutical
Post Ipo DebtJun 30, 2025
Amount Raised: $100,000,000
Altimmune

Gaithersburg, Maryland, United States

Altimmune focused on the development of products to stimulate robust and durable immune responses for the prevention.

BiotechnologyClinical TrialsHealth CareTest and Measurement
Post Ipo DebtMay 13, 2025
Amount Raised: $15,000,000
Job&Talent

Madrid, Madrid, Spain

Jobandtalent is an online staffing marketplace for finding and filling gig-type jobs.

EmploymentMarketplaceStaffing Agency
Series FApr 10, 2025
Amount Raised: $103,593,921
MoonLake Immunotherapeutics

Zug, Zug, Switzerland

MoonLake Immunotherapeutics is a clinical-stage biopharmaceuticals company.

Biotechnology
Post Ipo DebtApr 3, 2025
Amount Raised: $75,000,000
Savara Pharmaceuticals

Austin, Texas, United States

Savara Pharmaceuticals develops an inhaled antibiotic for MRSA infection in cystic fibrosis.

BiopharmaBiotechnologyPharmaceutical
Post Ipo DebtMar 26, 2025
Amount Raised: $30,000,000
Job&Talent

Madrid, Madrid, Spain

Jobandtalent is an online staffing marketplace for finding and filling gig-type jobs.

EmploymentMarketplaceStaffing Agency
Series FMar 25, 2025
Amount Raised: $99,255,690
Remodel Health

Indianapolis, Indiana, United States

Remodel Health delivers software to assist employers in managing health benefits and transitioning to ICHRA.

Employee BenefitsHealth CareSoftware
Series UnknownDec 19, 2024
Amount Raised: $100,000,000
Omio

Berlin, Berlin, Germany

Omio offers a multi-mode search tool that compares and combines rail, air, bus, and car for destinations.

InternetSearch EngineSoftwareTravelTravel Accommodations
Debt FinancingDec 2, 2024
Amount Raised: $120,000,000
Alector

San Francisco, California, United States

Alector is combining state-of-the-art antibody technology and recent discoveries in neuroimmunology and human genetics to develop novel.

BiotechnologyGeneticsHealth CareTherapeutics
Post Ipo DebtNov 14, 2024
Amount Raised: $50,000,000
Disc Medicine

Watertown, Massachusetts, United States

Disc Medicine is a biopharmaceutical company that develops therapies for hematologic diseases and rare blood disorders.

BiotechnologyHealth CareMedicalPharmaceuticalTherapeutics
Post Ipo DebtNov 8, 2024
Amount Raised: $225,500,000