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New Leaf Venture Partners

North America, New York, United States, New York

Description

New Leaf Venture Partners is a prominent venture capital firm based in New York City, specializing in investments within the healthcare technology sector. Established with a deep focus on life sciences, the firm targets companies developing breakthrough products and technologies that address significant unmet medical needs across therapeutics, medical devices, diagnostics, and digital health. With a long-standing history in the venture capital landscape, New Leaf Venture Partners has built a reputation for leveraging its team's extensive scientific, medical, and operational expertise to identify and nurture high-potential healthcare innovations.

The firm's investment strategy typically focuses on growth-stage companies, primarily participating in Series A, Series B, and Series C rounds. New Leaf Venture Partners seeks to partner with entrepreneurial teams, providing not only capital but also strategic guidance and industry connections to accelerate the development and commercialization of their portfolio companies. Their approach emphasizes a rigorous due diligence process and a hands-on partnership model, aiming to support companies from early development through clinical trials and market entry.

New Leaf Venture Partners manages substantial capital, with approximately $1.85 billion in assets under management across five dedicated funds, including their most recent New Leaf Ventures V, L.P. fund raised in 2022. This significant capital base enables them to make meaningful investments and provide follow-on funding to support their portfolio companies' long-term growth. The firm has demonstrated a prolific investment pace, having made 121 investments to date, and has frequently taken a leadership role, acting as a lead investor 36 times. While specific initial check sizes can vary based on the stage and capital requirements of the company, New Leaf Venture Partners typically deploys first checks ranging from $5 million to $25 million, reflecting their capacity to support substantial financing rounds in the capital-intensive healthcare industry.

Investor Profile

New Leaf Venture Partners has backed more than 168 startups, with 0 new investments in the last 12 months alone. The firm has led 41 rounds, about 24% of its total and boasts 57 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series Unknown, Series C rounds (top funding stages).
  • Majority of deals are located in United States, United Kingdom, Canada.
  • Strong thematic focus on Health Care, Biotechnology, Medical.
  • Typical check size: $5M – $25M.

Stage Focus

  • Series B (25%)
  • Series Unknown (18%)
  • Series C (17%)
  • Series A (13%)
  • Post Ipo Equity (7%)
  • Series D (7%)
  • Series E (4%)
  • Series F (3%)
  • Debt Financing (2%)
  • Series G (2%)

Country Focus

  • United States (92%)
  • United Kingdom (4%)
  • Canada (1%)
  • Ireland (1%)
  • Switzerland (1%)
  • Denmark (1%)
  • Israel (1%)

Industry Focus

  • Health Care
  • Biotechnology
  • Medical
  • Medical Device
  • Therapeutics
  • Pharmaceutical
  • Health Diagnostics
  • Biopharma
  • Software
  • Information Technology
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does New Leaf Venture Partners frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 26
SV Health Investors
North America, Massachusetts, United States, Boston
Co-Investments: 11
Canaan Partners
North America, California, United States, Menlo Park
Co-Investments: 17
Three Arch Partners
North America, California, United States, Portola Valley
Co-Investments: 14
Bay City Capital
North America, California, United States, San Francisco
Co-Investments: 9
5AM Ventures
North America, California, United States, Menlo Park
Co-Investments: 15
New Enterprise Associates
North America, California, United States, Menlo Park
Co-Investments: 11
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 13
Frazier Healthcare Partners
North America, Washington, United States, Seattle
Co-Investments: 10
Venrock
North America, California, United States, Palo Alto
Co-Investments: 10

Which angels does New Leaf Venture Partners often collaborate with?

David Baszucki
North America, California, United States, San Mateo
Shared Deals: 1
BD
North America, New York, United States, New York
Shared Deals: 1
Shmuel Cabilly
Asia, HaMerkaz, Israel, Rehovot
Shared Deals: 1
MM
Europe, Ile-de-France, France, Issy-les-moulineaux
Shared Deals: 1
JZ
North America, California, United States, Campbell
Shared Deals: 1
MS
North America, Florida, United States, Miami
Shared Deals: 1

What are some of recent deals done by New Leaf Venture Partners?

Truveris

New York, New York, United States

Truveris is a technology company driving transparency, access and lower costs across the prescription drug ecosystem.

Health CareInformation TechnologySaaSWellness
Series EMay 14, 2024
Amount Raised: $15,000,000
Qlaris Bio

Wellesley, Massachusetts, United States

Qlaris Bio focuses on developing first-in-class therapies for serious and debilitating ophthalmic diseases.

BiotechnologyHealth CareMedical
Series BApr 30, 2024
Amount Raised: $24,000,000
Flosonics

Sudbury, Ontario, Canada

Flosonics is a medical device company that focuses on developing non-invasive sensors to improve the management of critically ill patients.

Health CareMedicalMedical Device
Series CMar 19, 2024
Amount Raised: $20,000,000
Harpoon Therapeutics

South San Francisco, California, United States

Harpoon Therapeutics is a clinical-stage immunotherapy company focused on the development of novel T-cell recruiting biologic therapies.

BiotechnologyHealth CareTherapeutics
Post Ipo EquityOct 23, 2023
Amount Raised: $100,000,000
Arvist

Chicago, Illinois, United States

Arvist improves productivity in warehouses and distribution centers with real-time digital twins without new infrastructure investments

Artificial Intelligence (AI)Computer VisionLogisticsMachine LearningSupply Chain ManagementWarehousing
Pre SeedSep 10, 2023
Amount Raised: $1,000,000
Star Therapeutics

South San Francisco, California, United States

Star Therapeutics mission is to develop therapies for as many diseases as possible for millions of patients.

Health CareMedicalTherapeutics
Series CSep 5, 2023
Amount Raised: $90,000,000
Harpoon Therapeutics

South San Francisco, California, United States

Harpoon Therapeutics is a clinical-stage immunotherapy company focused on the development of novel T-cell recruiting biologic therapies.

BiotechnologyHealth CareTherapeutics
Post Ipo EquityMar 27, 2023
Amount Raised: $25,000,000
Arine

San Francisco, California, United States

Arine optimizes medications and improves human health through data-driven clinical services.

BiotechnologyHealth CareMedicalPharmaceutical
Series BAug 17, 2022
Amount Raised: $29,000,000
Star Therapeutics

South San Francisco, California, United States

Star Therapeutics mission is to develop therapies for as many diseases as possible for millions of patients.

Health CareMedicalTherapeutics
Series UnknownFeb 16, 2022
Amount Raised: $100,000,000
Asimily

Sunnyvale, California, United States

Asimily's IoMT risk remediation platform holistically secures the mission-critical healthcare devices that deliver safe and reliable care.

Cyber SecurityData VisualizationHealth CareHospitalSoftware
Series UnknownNov 2, 2021
Amount Raised: $10,000,000