TwentyTwo VC

TwentyTwo VC, established in 2022 and based in San Francisco, California, is an early-stage venture capital firm committed to funding companies that enhance present and future quality of life. The firm primarily targets pre-seed and seed-stage startups, aiming to identify and support foundational technologies and innovative business models at their earliest phases. Their investment philosophy is rooted in a broad interpretation of "quality of life," encompassing various sectors critical to societal advancement and individual well-being.

The firm's investment strategy is characterized by a flexible yet focused approach, with typical first check sizes ranging from $250,000 to $1,000,000. This capital is deployed across a diverse set of high-growth sectors, including Healthcare & Biotech, AI & SaaS, Climate Tech, and FinTech. TwentyTwo VC seeks out disruptive technologies and visionary founders who are addressing significant market needs and developing solutions with the potential for widespread positive impact. Their sector-agnostic yet theme-driven approach allows them to explore opportunities that might traditionally fall outside narrow vertical definitions, as long as they align with the core mission of improving quality of life.

Since its inception, TwentyTwo VC has built a nascent but growing portfolio, with at least five publicly disclosed investments on their website. Notable portfolio companies include Nourish, a digital health platform, and Kura Technologies, an augmented reality company. The firm emphasizes a hands-on approach, aiming to provide strategic guidance and operational support to its portfolio companies beyond just capital. By focusing on early-stage opportunities and maintaining a clear thematic alignment, TwentyTwo VC positions itself as a partner for founders building the next generation of impactful companies.