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Venrock Healthcare Capital Partners

North America, California, United States, Palo Alto

Description

Venrock Healthcare Capital Partners (VHCP) is a specialized investment firm focused exclusively on the healthcare sector, primarily targeting later-stage private companies and publicly traded entities. Distinct from the early-stage venture capital firm Venrock, VHCP employs a crossover investment strategy, providing growth capital, structured debt, and public equity investments. Based in Palo Alto, California, the firm leverages deep industry expertise to identify opportunities across biotechnology, pharmaceuticals, medical devices, and healthcare services.

VHCP's investment thesis centers on identifying companies with strong fundamentals, significant market potential, and clear paths to value creation, whether through clinical milestones, regulatory approvals, or market expansion. Their team comprises professionals with extensive backgrounds in science, medicine, and finance, enabling a rigorous due diligence process and informed decision-making. They often partner with management teams to navigate complex industry landscapes and accelerate growth.

The firm manages substantial capital, with recent funds like VHCP Flagship Fund V closing at $600 million in 2021, demonstrating their capacity for significant deployments. Their typical first check sizes for private companies or initial public market positions generally range from $10 million to $50 million, reflecting their focus on growth-stage and mature businesses. These investments are often part of larger financing rounds, including Series C, D, and beyond, as well as Private Investments in Public Equity (PIPEs).

VHCP's strategy allows them to be flexible across the capital structure, providing solutions tailored to the specific needs of healthcare companies, from pre-IPO growth rounds to public market support. This unique positioning enables them to participate in a broad spectrum of opportunities within the dynamic healthcare ecosystem, aiming to generate strong returns by backing innovative and impactful healthcare solutions.

Investor Profile

Venrock Healthcare Capital Partners has backed more than 81 startups, with 16 new investments in the last 12 months alone. The firm has led 22 rounds, about 27% of its total and boasts 45 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Post Ipo Equity, Series B, Series A rounds (top funding stages).
  • Majority of deals are located in United States, Canada, France.
  • Strong thematic focus on Biotechnology, Health Care, Therapeutics.
  • Led 7 rounds in the past year.
  • Typical check size: $10M – $50M.

Stage Focus

  • Post Ipo Equity (53%)
  • Series B (20%)
  • Series A (12%)
  • Series C (11%)
  • Series D (1%)
  • Series E (1%)
  • Undisclosed (1%)

Country Focus

  • United States (81%)
  • Canada (4%)
  • France (4%)
  • Switzerland (2%)
  • China (2%)
  • Ireland (2%)
  • Bermuda (1%)
  • Denmark (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Therapeutics
  • Pharmaceutical
  • Medical
  • Biopharma
  • Life Science
  • Medical Device
  • Oncology
  • Genetics
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Venrock Healthcare Capital Partners frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 17
RTW Investments
North America, New York, United States, New York
Co-Investments: 20
TCG Crossover
North America, California, United States, Palo Alto
Co-Investments: 18
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 23
Fairmount Funds Management
North America, Pennsylvania, United States, Philadelphia
Co-Investments: 17
Perceptive Advisors
North America, New York, United States, New York
Co-Investments: 20
Vivo Capital
North America, California, United States, Palo Alto
Co-Investments: 14
Logos Capital
North America, California, United States, San Francisco
Co-Investments: 21
Janus Henderson Investors
Europe, England, United Kingdom, London
Co-Investments: 15
Boxer Capital
North America, Florida, United States, Windermere
Co-Investments: 19

Which angels does Venrock Healthcare Capital Partners often collaborate with?

LW
North America, Washington, United States, Seattle
Shared Deals: 1
FB
North America, Ohio, United States, Columbus
Shared Deals: 1
BS
North America, Minnesota, United States, Minneapolis
Shared Deals: 1
SK
North America, California, United States, Los Angeles
Shared Deals: 1
Shared Deals: 1
RK
North America, California, United States, Los Angeles
Shared Deals: 1

What are some of recent deals done by Venrock Healthcare Capital Partners?

Vor Biopharma

Cambridge, Massachusetts, United States

Vor Biopharma is an immuno-oncology company that develops therapies for treating cancer.

BiotechnologyHealth CareOncologyPharmaceutical
Post Ipo EquityJun 24, 2025
Amount Raised: $175,000,000
Crescent Biopharma

Rockville, Maryland, United States

Crescent Biopharma is a biotechnology firm focused on developing novel precision-engineered medicines.

BiotechnologyHealth CareMedical Device
Post Ipo EquityJun 16, 2025
Amount Raised: $200,000,000
ORIC Pharmaceuticals

South San Francisco, California, United States

ORIC Pharmaceuticals is a biopharmaceutical company that develops treatments that target the causes of therapeutic resistance.

BiopharmaBiotechnologyHealth CarePharmaceuticalTherapeutics
Post Ipo EquityMay 28, 2025
Amount Raised: $125,000,000
CytomX Therapeutics

South San Francisco, California, United States

CytomX Therapeutics is a biotechnology company that focuses on developing proteolytically-activated antibodies.

BiotechnologyHealth CarePharmaceuticalTherapeutics
Post Ipo EquityMay 12, 2025
Amount Raised: $100,000,000
AIRNA

Cambridge, Massachusetts, United States

AIRNA develops RNA editing technologies to create medicines for various diseases.

BiotechnologyHealth CareMedical
Series BApr 1, 2025
Amount Raised: $155,000,000
Surrozen

South San Francisco, California, United States

Surrozen is a biopharmaceutical that focuses on unlocking the body’s regenerative power to treat injury and disease.

BiotechnologyEmergency MedicineHealth Care
Post Ipo EquityMar 24, 2025
Amount Raised: $175,000,000
Solid Biosciences

Marlborough, Massachusetts, United States

Solid Biosciences is a life science company that conducts research for the treatment of Duchenne muscular dystrophy.

BiotechnologyGeneticsHealth CareMedical
Post Ipo EquityFeb 18, 2025
Amount Raised: $200,000,000
Timberlyne Therapeutics

San Diego, California, United States

Timberlyne Therapeutics is a biopharmaceutical company that develops therapies for autoimmune diseases.

BiopharmaBiotechnologyHealth Care
Series AJan 9, 2025
Amount Raised: $180,000,000
ADCendo

Copenhagen, Hovedstaden, Denmark

ADCendo ApS is a biotech company dedicated to developing new types of anti-cancer drugs.

BiotechnologyHealth Care
Series BNov 25, 2024
Amount Raised: $135,000,000
Cidara Therapeutics

San Diego, California, United States

Cidara Therapeutics is a biotechnology company that specializes in the fields of healthcare and therapeutics.

BiotechnologyHealth CareTherapeutics
Post Ipo EquityNov 21, 2024
Amount Raised: $105,000,000