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Mass General Brigham Ventures

North America, Massachusetts, United States, Cambridge

Description

Mass General Brigham Ventures (MGBV) operates as the strategic venture capital arm of Mass General Brigham, a leading integrated academic healthcare system based in Cambridge, Massachusetts. Leveraging the extensive clinical and research capabilities of its parent organization, including renowned institutions like Massachusetts General Hospital and Brigham and Women's Hospital, MGBV focuses on investing in early-stage life science and healthcare companies. Their investment thesis is deeply rooted in identifying innovations that can address unmet medical needs and improve patient care, often originating from or aligning with the research priorities within the Mass General Brigham ecosystem.

MGBV's investment scope spans a broad spectrum of healthcare innovation, encompassing therapeutics, medical devices, diagnostics, digital health, and healthcare IT. Beyond providing capital, the firm distinguishes itself by offering portfolio companies unparalleled access to clinical expertise, research infrastructure, and strategic guidance from within the Mass General Brigham network. This unique value proposition allows MGBV to not only provide financial backing but also to accelerate the development and validation of promising technologies through clinical collaboration and real-world application.

Since its inception, Mass General Brigham Ventures has demonstrated a robust investment pace, having invested in over 60 companies. Their typical initial check sizes range from $1 million to $5 million, often participating in Series A and Series B rounds alongside other prominent venture capital firms. This strategic approach underscores their commitment to fostering innovation that can be integrated into or benefit from a large-scale healthcare system, aiming to drive both financial returns and significant advancements in patient health.

Investor Profile

Mass General Brigham Ventures has backed more than 33 startups, with 3 new investments in the last 12 months alone. The firm has led 4 rounds, about 12% of its total and boasts 2 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series A, Series B, Seed rounds (top funding stages).
  • Majority of deals are located in United States, France.
  • Strong thematic focus on Health Care, Biotechnology, Therapeutics.
  • Typical check size: $1M – $5M.

Stage Focus

  • Series A (39%)
  • Series B (33%)
  • Seed (18%)
  • Series C (9%)

Country Focus

  • United States (94%)
  • France (6%)

Industry Focus

  • Health Care
  • Biotechnology
  • Therapeutics
  • Medical
  • Pharmaceutical
  • Life Science
  • Wellness
  • Hospital
  • Mental Health
  • Precision Medicine
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Mass General Brigham Ventures frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 4
Sectoral Asset Management
North America, Quebec, Canada, Montréal
Co-Investments: 4
Alexandria Venture Investments
North America, California, United States, Pasadena
Co-Investments: 5
Google Ventures
North America, California, United States, Mountain View
Co-Investments: 5
Casdin Capital
North America, New York, United States, New York
Co-Investments: 4
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 5
F-Prime Capital
North America, Massachusetts, United States, Cambridge
Co-Investments: 4
Pontifax
Asia, Tel Aviv, Israel, Herzliya
Co-Investments: 5
Sanofi Ventures
North America, Massachusetts, United States, Cambridge
Co-Investments: 5
ARCH Venture Partners
North America, Illinois, United States, Chicago
Co-Investments: 4

What are some of recent deals done by Mass General Brigham Ventures?

Carta Healthcare

San Francisco, California, United States

Carta Healthcare empowers hospitals to personalize the delivery of care to the individual needs of each patient.

DeliveryHealth CareHospitalMachine Learning
Series BMay 7, 2025
Amount Raised: $18,250,000
Abcuro

Newton, Massachusetts, United States

Abcuro develops immunotherapies to treat autoimmunity and cancer.

BiotechnologyHealth CareMedicalTherapeutics
Series CFeb 12, 2025
Amount Raised: $200,000,000
Rippl Care

Seattle, Washington, United States

Rippl Care is a mental health company committed to assisting seniors who suffer from dementia and other neurocognitive disorders.

Elder CareHealth CareHealth DiagnosticsMental Health
Series AOct 2, 2024
Amount Raised: $23,000,000
Tuesday Health

Nashville, Tennessee, United States

Tuesday Health empowers lives through supportive care by easing the symptoms and stress of serious illness.

Health CareHospitalWellness
Series AMay 21, 2024
Amount Raised: $60,000,000
InStride Health

Boston, Massachusetts, United States

InStride Health provides evidence-based OCD and anxiety treatment to keep kids and teenagers engaged along the way.

Health CareMental HealthWellness
Series BMar 27, 2024
Amount Raised: $30,000,000
Nocion Therapeutics

Cambridge, Massachusetts, United States

Nocion Therapeutics is a developer of novel pharmaceuticals intended to treat the conditions arising from neurogenic inflammation.

BiotechnologyHealth CareMedical
Series BMar 4, 2024
Amount Raised: $62,000,000
Claris Biotherapeutics

Jersey City, New Jersey, United States

Claris Biotherapeutics develops a topical formulation intended to cure corneal wounds, ulcers, and scars.

BiotechnologyHealth CareTherapeutics
Series AJan 4, 2024
Amount Raised: $57,000,000
ROME Therapeutics

Cambridge, Massachusetts, United States

ROME Therapeutics is developing novel therapies for cancer and autoimmune diseases by harnessing the power of the repeatome.

BiotechnologyHealth CarePharmaceutical
Series BSep 12, 2023
Amount Raised: $72,000,000
Abcuro

Newton, Massachusetts, United States

Abcuro develops immunotherapies to treat autoimmunity and cancer.

BiotechnologyHealth CareMedicalTherapeutics
Series BAug 17, 2023
Amount Raised: $155,000,000
Violet Therapeutics

Cambridge, Massachusetts, United States

Violet Therapeutics is a pre-clinical stage company leveraging first-in-class platforms to identify, map, and mine the cellular connectome.

Health CareMedicalTherapeutics
SeedMay 5, 2023
Amount Raised: $10,600,000