ZW

Zach Weinberg

North America, New York, United States, New York

Description

Zach Weinberg is a highly successful entrepreneur turned prolific angel investor, primarily known for his significant contributions to the ad tech and healthcare technology sectors. He first made his mark as the Co-Founder, President, and COO of Invite Media, an advertising technology company based in New York City, which was acquired by Google in 2010. Following this success, Weinberg co-founded Flatiron Health in 2012, a company dedicated to organizing and analyzing real-world oncology data to improve cancer care. Flatiron Health achieved a major exit when it was acquired by Roche for an impressive $1.9 billion in 2018, solidifying Weinberg's reputation as a visionary builder.

Leveraging his deep operational experience and substantial capital from his exits, Weinberg transitioned into an active angel investing role, primarily focusing on early-stage companies. His investment thesis heavily leans into healthcare technology, B2B SaaS, and data-driven solutions, often seeking out companies that aim to solve complex problems within large, established industries. He is particularly drawn to founders with strong product visions and the potential to disrupt traditional markets.

As an angel investor, Weinberg is known for being hands-on and strategic, often taking on lead investor roles. According to Crunchbase, he has made over 50 investments and has been a lead investor in 18 of those deals, demonstrating his commitment to actively shaping the trajectory of his portfolio companies. His investments span a wide range of innovative healthcare startups, including notable names like Maven Clinic, Capable Health, Ribbon Health, and Cohere Health. Weinberg brings not only capital but also invaluable guidance, leveraging his experience scaling two successful technology companies from inception to significant exits, making him a highly sought-after partner for nascent ventures.

Investor Profile

Zach Weinberg has backed more than 62 startups, with 1 new investments in the last 12 months alone. The firm has led 0 rounds, about 0% of its total and boasts 17 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Seed, Series A, Pre Seed rounds (top funding stages).
  • Majority of deals are located in United States, United Kingdom, Israel.
  • Strong thematic focus on Software, Health Care, Artificial Intelligence (AI).
  • Typical check size: $100K – $750K.

Stage Focus

  • Seed (56%)
  • Series A (26%)
  • Pre Seed (8%)
  • Series B (5%)
  • Angel (3%)
  • Series Unknown (2%)

Country Focus

  • United States (97%)
  • United Kingdom (2%)
  • Israel (2%)

Industry Focus

  • Software
  • Health Care
  • Artificial Intelligence (Ai)
  • Saas
  • Medical
  • Financial Services
  • Fintech
  • Analytics
  • Enterprise Software
  • E-commerce
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Zach Weinberg frequently co-invest with?

Two Sigma Ventures
North America, New York, United States, New York
Co-Investments: 4
Bossa Invest
South America, Sao Paulo, Brazil, São Paulo
Co-Investments: 3
Founder Collective
North America, Massachusetts, United States, Cambridge
Co-Investments: 6
Great Oaks Venture Capital
North America, New York, United States, New York
Co-Investments: 11
SV Angel
North America, California, United States, San Francisco
Co-Investments: 5
BoxGroup
North America, New York, United States, New York
Co-Investments: 7
Operator Partners
North America, New York, United States, New York
Co-Investments: 7
Dynamic Loop Capital
Asia, Tel Aviv, Israel, Herzliyya
Co-Investments: 4
Alumni Ventures
North America, New Hampshire, United States, Manchester
Co-Investments: 5
Lerer Hippeau
North America, New York, United States, New York
Co-Investments: 6

Which angels does Zach Weinberg often collaborate with?

NB
North America, New York, United States, New York
Shared Deals: 2
NT
North America, New York, United States, New York
Shared Deals: 45
David Tisch
North America, New York, United States, New York
Shared Deals: 4
JA
North America, New York, United States, New York
Shared Deals: 2
GS
North America, New York, United States, New York
Shared Deals: 4
Assaf Wand
Asia, Tel Aviv, Israel
Shared Deals: 2
BL
North America, California, United States, Menlo Park
Shared Deals: 2
MK
North America, New York, United States, New York
Shared Deals: 3
SB
North America, New York, United States, New York
Shared Deals: 5
VG
North America, New York, United States, New York
Shared Deals: 3

What are some of recent deals done by Zach Weinberg?

Crosby

New York, New York, United States

Crosby is a company with programmers from Ramp, Vanta, Meta, and Google joining attorneys.

Artificial Intelligence (AI)Software
SeedJun 17, 2025
Amount Raised: $5,800,000
Scoop

San Francisco, California, United States

Your in-office days should be awesome days. Instant, effortless planning tools for hybrid employees.

Productivity ToolsSoftwareVirtual Workforce
SeedNov 17, 2022
Amount Raised: $8,000,000
Overwatch Research

Belfast, Belfast, United Kingdom

Overwatch Research provides an all-in-one experimental tracking software for vivo research.

Software
SeedOct 19, 2021
Amount Raised: $3,500,000
Iterative Scopes

Cambridge, Massachusetts, United States

Iterative Scopes delivers tools for physicians and life sciences in colorectal cancer and inflammatory bowel disease space.

Computer VisionHealth CareHealth DiagnosticsMedical
Series AAug 3, 2021
Amount Raised: $30,000,000
Connie Health

Boston, Massachusetts, United States

Connie Health empowers older Americans to make confident, worry-free healthcare decisions.

Health Care
Series AJul 28, 2021
Amount Raised: $13,000,000
Nym

New York, New York, United States

Nym transforms revenue cycle management by fully automating the medical coding process.

AnalyticsBioinformaticsData Center AutomationHealth CareProductivity ToolsSoftware
Series AJul 27, 2021
Amount Raised: $25,000,000
HumanFirst

San Francisco, California, United States

HumanFirst accelerates the adoption of patient-centered clinical trials using precision digital measures (e.g., digital biomarkers and eCOA)

Health Care
Series AMay 31, 2021
Amount Raised: $12,000,000
RightBound

Kirkland, Washington, United States

RightBound develops a sales platform that automates and streamlines the sales process.

B2BSaaSSales Automation
Series AMay 26, 2021
Amount Raised: $8,900,000
Memora Health

San Francisco, California, United States

The leading intelligent care enablement platform to simplify how patients and clinicians navigate complex care delivery.

Health CareOutpatient CareSoftware
Series UnknownMay 11, 2021
Amount Raised: $10,500,000
Small Door

New York, New York, United States

Small Door is a membership-based veterinary service that offers surgery, wellness, and preventative care.

Health CareMedicalPetVeterinary
Series AApr 15, 2021
Amount Raised: $20,000,000