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Transformation Capital

North America, Massachusetts, United States, Boston

Description

Transformation Capital is a prominent growth equity firm based in Boston, Massachusetts, exclusively focused on investing in innovative healthcare IT and services companies. Established with a clear vision to support businesses that are fundamentally transforming the healthcare landscape, the firm targets growth-stage companies that have demonstrated product-market fit and possess significant revenue traction, typically exceeding $10 million annually. Their investment philosophy centers on partnering with experienced management teams to accelerate growth and scale operations, often serving as the initial institutional capital provider in their respective categories.

The firm has demonstrated a remarkable trajectory of growth in its fundraising efforts, reflecting strong investor confidence in its specialized strategy. Transformation Capital successfully closed its fourth fund, Fund IV, at an impressive $1.2 billion in 2023. This significant capital raise followed a series of increasingly larger funds, including Fund III, which closed at $600 million in 2021, and Fund II at $300 million in 2019. This consistent increase in fund size underscores their expanding capacity to deploy substantial capital into promising healthcare technology ventures.

Transformation Capital typically deploys substantial first cheques, with a reported range of $50 million to $150 million per company. This substantial investment size allows them to take meaningful stakes in their portfolio companies and provide the necessary capital for aggressive expansion, market penetration, and product development. Their portfolio includes companies that are at the forefront of digital health innovation, ranging from clinical workflow solutions and patient engagement platforms to data analytics and value-based care enablers, all aimed at improving efficiency, access, and outcomes within the complex healthcare ecosystem.

Investor Profile

Transformation Capital has backed more than 56 startups, with 5 new investments in the last 12 months alone. The firm has led 28 rounds, about 50% of its total and boasts 7 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series C, Series B, Series Unknown rounds (top funding stages).
  • Majority of deals are located in United States.
  • Strong thematic focus on Health Care, Medical, Software.
  • Led 5 rounds in the past year.
  • Typical check size: $50M – $150M.

Stage Focus

  • Series C (27%)
  • Series B (25%)
  • Series Unknown (20%)
  • Series D (14%)
  • Series A (4%)
  • Private Equity (4%)
  • Seed (4%)
  • Series G (2%)
  • Series E (2%)

Country Focus

  • United States (100%)

Industry Focus

  • Health Care
  • Medical
  • Software
  • Artificial Intelligence (Ai)
  • Therapeutics
  • Wellness
  • Biotechnology
  • Life Science
  • Hospital
  • Mhealth
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Transformation Capital frequently co-invest with?

General Catalyst
North America, Massachusetts, United States, Cambridge
Co-Investments: 8
Google Ventures
North America, California, United States, Mountain View
Co-Investments: 4
SignalFire
North America, California, United States, San Francisco
Co-Investments: 3
Casdin Capital
North America, New York, United States, New York
Co-Investments: 4
Frist Cressey Ventures
North America, Tennessee, United States, Nashville
Co-Investments: 5
Optum Ventures
North America, Massachusetts, United States, Boston
Co-Investments: 4
Andreessen Horowitz
North America, California, United States, Menlo Park
Co-Investments: 3
Common Fund
North America, Connecticut, United States, Wilton
Co-Investments: 5
HLM Venture Partners
North America, Massachusetts, United States, Boston
Co-Investments: 4
Khosla Ventures
North America, California, United States, Menlo Park
Co-Investments: 4

Which angels does Transformation Capital often collaborate with?

AS
North America, New York, United States, New York
Shared Deals: 1
AP
North America, California, United States, San Francisco
Shared Deals: 1
PT
North America, California, United States, San Francisco
Shared Deals: 1
NX
North America, California, United States, San Francisco
Shared Deals: 2
Dak Prescott
North America, Louisiana, United States, Sulphur
Shared Deals: 1
AK
North America, New York, United States, New York
Shared Deals: 1
AW
North America, California, United States, San Francisco
Shared Deals: 1
JB
North America, Iowa, United States, Ames
Shared Deals: 1
JH
North America, California, United States, Los Angeles
Shared Deals: 1
SW
North America, California, United States, Mountain View
Shared Deals: 1

What are some of recent deals done by Transformation Capital?

Arbital Health

Santa Rosa, California, United States

Arbital Health provides neutral adjudication services for outcomes-based healthcare contracts.

Health CareMedicalWellness
Series BJul 29, 2025
Amount Raised: $31,000,000
Certify

New York, New York, United States

Certify is an API-driven platform automating all stages of provider network management: licensing, enrollment, credentialing, monitoring.

Developer APIsHealth CareSoftware
Series BJun 26, 2025
Amount Raised: $40,000,000
Local Infusion

Nashville, Tennessee, United States

Technology-driven infusion therapy company

Health CarePharmaceuticalTherapeutics
Series BJun 17, 2025
Amount Raised: $30,000,000
World Class Health

New York, New York, United States

World Class Health is a Hospitals and Health Care company.

Health CareHospital
Series UnknownApr 24, 2025
Amount Raised: $10,000,000
Rad AI

San Francisco, California, United States

Rad AI develops software that uses AI to automate radiology report writing, aiming to enhance accuracy and reduce radiologist burnout.

Artificial Intelligence (AI)Enterprise SoftwareHealth Care
Series CJan 25, 2025
Amount Raised: $60,000,000
Citizen Health

San Mateo, California, United States

Citizen Health is building an AI-based consumer health platform that leverages data to accelerate care and treatments for rare diseases.

Artificial Intelligence (AI)Big DataConsumer SoftwareInformation TechnologyLife Science
SeedNov 19, 2024
Amount Raised: $14,500,000
TMRW Life Sciences

New York, New York, United States

TMRW Life Sciences provides an integrated platform for automated, software-guided cryospecimen management.

BiotechnologyHealth CareLife ScienceSoftware
Series DJul 12, 2024
Amount Raised: $28,172,940
Amino

San Francisco, California, United States

Amino is a data-driven healthcare guidance platform that helps companies and their employees navigate the complex US healthcare system.

Employee BenefitsFinancial ServicesHealth CareWellness
Series UnknownMay 22, 2024
Amount Raised: $10,000,000
SmarterDx

New York, New York, United States

SmarterDx is a clinical AI company that develops automated pre-bill review tech to help hospitals maintain revenue integrity.

Artificial Intelligence (AI)Health CareHospitalInformation Technology
Series BMay 14, 2024
Amount Raised: $50,000,000
Grow Therapy

New York, New York, United States

Grow Therapy is a provider-centric mental health technology company improving access to high-quality mental healthcare.

Health CareMedicalMental HealthTherapeutics
Series CApr 8, 2024
Amount Raised: $88,000,000